(Q39881846)

English

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.

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scholarly article

1 reference

Europe PubMed Central

15 September 2017

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. (English)

1 reference

Europe PubMed Central

15 September 2017

1 reference

based on heuristic

inferred from title

Matthias Hentze

4

1 reference

Europe PubMed Central

15 September 2017

Guillem Casanovas

object named as

Guillem Casanovas

1

0 references

Katarzyna Mleczko-Sanecka

object named as

Katarzyna Mleczko-Sanecka

2

0 references

Martina U Muckenthaler

5

object named as

Martina U Muckenthaler

1 reference

Europe PubMed Central

15 September 2017

author name string

Sandro Altamura

3

1 reference

Europe PubMed Central

15 September 2017

publication date

20 February 2009

1 reference

Europe PubMed Central

15 September 2017

Journal of Molecular Medicine

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Europe PubMed Central

15 September 2017

87

1 reference

Europe PubMed Central

15 September 2017

5

1 reference

Europe PubMed Central

15 September 2017

471-480

1 reference

Europe PubMed Central

15 September 2017

https://scigraph.springernature.com/pub.10.1007/s00109-009-0447-2

0 references

Hepcidin is decreased in TFR2 hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepcidin: iron-hormone and anti-microbial peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces hepcidin expression through STAT3

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forging a field: the golden age of iron biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distal location of the iron responsive region of the hepcidin promoter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MatInspector and beyond: promoter analysis based on transcription factor binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19229506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00109-009-0447-2

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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