(Q39883889)

15 September 2017

title

Significant correction of pathology in brains of twitcher mice following injection of genetically modified mouse neural progenitor cells (English)

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15 September 2017

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Michelina Strazza

1

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15 September 2017

Alice Luddi

2

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15 September 2017

Marica Carbone

3

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15 September 2017

Mohammad A Rafi

4

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15 September 2017

Elvira Costantino-Ceccarini

5

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15 September 2017

David A Wenger

6

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15 September 2017

publication date

12 February 2009

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Molecular Genetics and Metabolism

15 September 2017

published in

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15 September 2017

volume

97

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15 September 2017

issue

1

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15 September 2017

page(s)

27-34

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An apoptotic depletion of oligodendrocytes in the twitcher, a murine model of globoid cell leukodystrophy.

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Psychosine is as potent an inducer of cell death as C6-ceramide in cultured fibroblasts and in MOCH-1 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Psychosine-induced apoptosis in a mouse oligodendrocyte progenitor cell line is mediated by caspase activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Hematopoietic stem-cell transplantation in globoid-cell leukodystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

The Twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Generation of a mouse with low galactocerebrosidase activity by gene targeting: a new model of globoid cell leukodystrophy (Krabbe disease).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Prolonged survival and remyelination after hematopoietic cell transplantation in the twitcher mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Hematopoietic cell transplantation in murine globoid cell leukodystrophy (the twitcher mouse): effects on levels of galactosylceramidase, psychosine, and galactocerebrosides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Effect of bone marrow transplantation on enzyme levels and clinical course in the neurologically affected twitcher mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Cloning and expression of cDNA encoding human galactocerebrosidase, the enzyme deficient in globoid cell leukodystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Retroviral vector-mediated transfer of the galactocerebrosidase (GALC) cDNA leads to overexpression and transfer of GALC activity to neighboring cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Correction of the galactocerebrosidase deficiency in globoid cell leukodystrophy-cultured cells by SL3-3 retroviral-mediated gene transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Retroviral-mediated transfer of the galactocerebrosidase gene in neural progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Transduction of cultured oligodendrocytes from normal and twitcher mice by a retroviral vector containing human galactocerebrosidase (GALC) cDNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Retrovirus-mediated gene transfer and galactocerebrosidase uptake into twitcher glial cells results in appropriate localization and phenotype correction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Intraventricular administration of recombinant adenovirus to neonatal twitcher mouse leads to clinicopathological improvements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

GALC transduction leads to morphological improvement of the twitcher oligodendrocytes in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Transgenic rescue of Krabbe disease in the twitcher mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

AAV-mediated expression of galactocerebrosidase in brain results in attenuated symptoms and extended life span in murine models of globoid cell leukodystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

AAV2/5 vector expressing galactocerebrosidase ameliorates CNS disease in the murine model of globoid-cell leukodystrophy more efficiently than AAV2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Design and optimization of lentiviral vectors for transfer of GALC expression in Twitcher brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Central nervous system-directed AAV2/5-mediated gene therapy synergizes with bone marrow transplantation in the murine model of globoid-cell leukodystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Widespread engraftment of neural progenitor and stem-like cells throughout the mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Enzyme replacement therapy results in substantial improvements in early clinical phenotype in a mouse model of globoid cell leukodystrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

A Stable Bovine Papillomavirus Hybrid Plasmid That Expresses a Dominant Selective Trait

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Glial progenitors in the CNS and possible lineage relationships among them

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

Stem cells for the treatment of neurological disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2009.01.005

10.1016/J.YMGME.2009.01.005

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

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