(Q39884109)

15 September 2017

Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells (English)

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15 September 2017

3

Lynne E Maquat

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15 September 2017

Daiki Matsuda

1

1 reference

PubMed ID

19215759

15 September 2017

Hanae Sato

series ordinal

2

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PubMed ID

19215759

15 September 2017

language of work or name

English

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publication date

1 January 2008

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15 September 2017

Methods in Enzymology

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15 September 2017

449

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15 September 2017

177-201

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A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

15 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

An alternative branch of the nonsense-mediated decay pathway

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The nonsense-mediated decay RNA surveillance pathway

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Identification and characterization of a nuclear pore complex protein

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Translation is required to remove Y14 from mRNAs in the cytoplasm

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The pleckstrin homology (PH) domain-interacting protein couples the insulin receptor substrate 1 PH domain to insulin signaling pathways leading to mitogenesis and GLUT4 translocation

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense-mediated mRNA decay in health and disease

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Y14 and hUpf3b form an NMD-activating complex

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense-mediated decay approaches the clinic

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Translational repression by a novel partner of human poly(A) binding protein, Paip2

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

A gene-targeted mouse model for familial hypobetalipoproteinemia. Low levels of apolipoprotein B mRNA in association with a nonsense mutation in exon 26 of the apolipoprotein B gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Staufen1 regulates diverse classes of mammalian transcripts

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The evolving roles of alternative splicing

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The protein Mago provides a link between splicing and mRNA localization.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

eIF4G is required for the pioneer round of translation in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Expression of six mouse major urinary protein genes in the mammary, parotid, sublingual, submaxillary, and lachrymal glands and in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

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https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2808%2902409-9

7 January 2021

10.1016/S0076-6879(08)02409-9

Identifiers

DOI

1 reference

15 September 2017

1 reference

PubMed ID

19215759