(Q39912845)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Src phosphorylation of micro-receptor is responsible for the receptor switching from an inhibitory to a stimulatory signal (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Lei Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hui Zhao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Yu Qiu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Horace H Loh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

24 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

1990-2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

17 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2629085/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Ligand-specific receptor states: implications for opiate receptor signalling and regulation

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

1 reference

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Src kinase regulation by phosphorylation and dephosphorylation

22 September 2017

1 reference

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Morphine alters the selective association between mu-opioid receptors and specific RGS proteins in mouse periaqueductal gray matter

22 September 2017

1 reference

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Internalization and Src activity regulate the time course of ERK activation by delta opioid receptor ligands.

22 September 2017

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beta-arrestins: traffic cops of cell signaling

22 September 2017

1 reference

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Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor

22 September 2017

1 reference

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Kappa-opioid receptor signals through Src and focal adhesion kinase to stimulate c-Jun N-terminal kinases in transfected COS-7 cells and human monocytic THP-1 cells

22 September 2017

1 reference

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Essential role for RGS9 in opiate action

22 September 2017

1 reference

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GIT1 Mediates Src-dependent Activation of Phospholipase Cγ by Angiotensin II and Epidermal Growth Factor

22 September 2017

1 reference

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Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling

22 September 2017

1 reference

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Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

22 September 2017

1 reference

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Rac and Cdc42-dependent regulation of c-Jun N-terminal kinases by the delta-opioid receptor

22 September 2017

1 reference

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Functional relevance of G-protein-coupled-receptor-associated proteins, exemplified by receptor-activity-modifying proteins (RAMPs).

22 September 2017

1 reference

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G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

22 September 2017

1 reference

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Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal

22 September 2017

1 reference

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Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2

22 September 2017

1 reference

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Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Chronic morphine induces the concomitant phosphorylation and altered association of multiple signaling proteins: a novel mechanism for modulating cell signaling

22 September 2017

1 reference

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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

22 September 2017

1 reference

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Stimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase signaling pathway

22 September 2017

1 reference

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Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation

22 September 2017

1 reference

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Molecular mechanisms and regulation of opioid receptor signaling

22 September 2017

1 reference

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Mutational analysis of the structure and function of opioid receptors

22 September 2017

1 reference

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Heptahelical receptor signaling: beyond the G protein paradigm.

22 September 2017

1 reference

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Src family kinases are required for integrin but not PDGFR signal transduction.

22 September 2017

1 reference

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Evidence for a regulated interaction between heterotrimeric G proteins and caveolin

22 September 2017

1 reference

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Cellular and molecular mechanisms of drug dependence

22 September 2017

1 reference

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Gz-mediated hormonal inhibition of cyclic AMP accumulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance

22 September 2017

1 reference

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Characteristics of a human cell line transformed by DNA from human adenovirus type 5

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Opiate-dependent modulation of adenylate cyclase

22 September 2017

1 reference

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RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Src tyrosine kinase is a novel direct effector of G proteins.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Mutation of tyrosine 318 (Y318F) in the delta-opioid receptor attenuates tyrosine phosphorylation, agonist-dependent receptor internalization, and mitogen-activated protein kinase activation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

The stimulatory effect of opioids on mitogen-activated protein kinase in Chinese hamster ovary cells transfected to express mu-opioid receptors.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Chronic opioid treatment induces adenylyl cyclase V superactivation. Involvement of Gbetagamma

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Dual effects of DAMGO [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin and CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2) on adenylyl cyclase activity: implications for mu-opioid receptor Gs coupling

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Inverse agonist up-regulates the constitutively active D3.49(164)Q mutant of the rat mu-opioid receptor by stabilizing the structure and blocking constitutive internalization and down-regulation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

The regulator of G protein signaling RGS4 selectively enhances alpha 2A-adreoreceptor stimulation of the GTPase activity of Go1alpha and Gi2alpha

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Loss of opiate receptor activity in neuroblastoma X glioma NG108-15 hybrid cells after chronic opiate treatment. A multiple-step process

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Beta-arrestin2 and c-Src regulate the constitutive activity and recycling of mu opioid receptors in dorsal root ganglion neurons.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Adenylyl cyclase superactivation induced by long-term treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Role of Src family kinase in the rewarding effect and hyperlocomotion induced by morphine

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Coupling of M(2) muscarinic receptors to Src activation in cultured canine colonic smooth muscle cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization*.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Chronic morphine augments adenylyl cyclase phosphorylation: relevance to altered signaling during tolerance/dependence

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Opiate-induced adenylyl cyclase superactivation is isozyme-specific.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Opiate receptor down-regulation and desensitization in neuroblastoma X glioma NG108-15 hybrid cells are two separate cellular adaptation processes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2629085

Inhibition of AC-II activity following chronic agonist exposure is modulated by phosphorylation

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19029294

12 December 2020

inferred from PubMed ID database lookup

Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19029294

12 December 2020

inferred from PubMed ID database lookup

Bradykinin-induced collapse of rat pheochromocytoma (PC12) cell growth cones: a role for tyrosine kinase activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19029294

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M807971200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029294%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference