(Q39916831)

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Effect of dopamine D3 receptor gene polymorphisms and clozapine treatment response: exploratory analysis of nine polymorphisms and meta-analysis of the Ser9Gly variant

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Europe PubMed Central

15 September 2017

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Effect of dopamine D3 receptor gene polymorphisms and clozapine treatment response: exploratory analysis of nine polymorphisms and meta-analysis of the Ser9Gly variant (English)

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Europe PubMed Central

15 September 2017

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Steven G. Potkin

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Europe PubMed Central

15 September 2017

author name string

R Hwang

1

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Europe PubMed Central

15 September 2017

C Zai

2

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Europe PubMed Central

15 September 2017

A Tiwari

3

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Europe PubMed Central

15 September 2017

D J Müller

4

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Europe PubMed Central

15 September 2017

M J Arranz

5

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Europe PubMed Central

15 September 2017

A G Morris

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Europe PubMed Central

15 September 2017

P J McKenna

7

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Europe PubMed Central

15 September 2017

J Munro

8

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Europe PubMed Central

15 September 2017

J A Lieberman

10

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Europe PubMed Central

15 September 2017

H Y Meltzer

11

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15 September 2017

J L Kennedy

12

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22 December 2009

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15 September 2017

The Pharmacogenomics Journal

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10

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15 September 2017

200-218

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15 September 2017

3

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Europe PubMed Central

15 September 2017

https://scigraph.springernature.com/pub.10.1038/tpj.2009.65

0 references

Pharmacogenetics of psychotropic drug response

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Effectiveness of antipsychotic drugs in patients with chronic schizophrenia

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Olanzapine: concordant response in monozygotic twins with schizophrenia

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Half a century of antipsychotics and still a central role for dopamine D2 receptors

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Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations

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The Mechanism of Action of Novel Antipsychotic Drugs

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The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders

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Distribution of dopamine D3 receptor expressing neurons in the human forebrain: comparison with D2 receptor expressing neurons

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Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study.

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D3 receptors and the actions of neuroleptics in the ventral striatopallidal system of schizophrenics

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Differential effects of clozapine and haloperidol on dopamine receptor mRNA expression in rat striatum and cortex.

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Organization of dopamine D1 and D2 receptors in human striatum: receptor autoradiographic studies in Huntington's disease and schizophrenia

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Effects of dopamine D3 receptor antagonists on spontaneous and agonist-reduced motor activity in NMRI mice and Wistar rats: comparative study with nafadotride, U 99194A and SB 277011.

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KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia

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Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110

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Role of dopamine D3 receptors in the expression of conditioned fear in rats

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Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats.

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REM sleep and cortisol responses to scopolamine during depression and remission in women

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The dopamine D3 antagonist U-99194A maleate increases social behaviors of isolation-induced aggressive male mice

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Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention

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Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats

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Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine

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Clozapine-, but not haloperidol-, induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors.

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Effect of the selective dopamine D3 receptor antagonist SB-277011-A on regional c-Fos-like expression in rat forebrain

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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

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A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor.

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Proposed schizophrenia-related gene polymorphism: expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system

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The ser9gly SNP in the dopamine D3 receptor causes a shift from cAMP related to PGE2 related signal transduction mechanisms in transfected CHO cells

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Meta-analysis of DRD3 gene and schizophrenia: ethnic heterogeneity and significant association in Caucasians.

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Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis

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A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia.

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Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia

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The Ser9Gly polymorphism of the dopamine D3 receptor gene and risk of schizophrenia: an association study and a large meta-analysis.

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Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations: evidence from a case-control study and meta-analysis

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Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

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A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies

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The International HapMap Project

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Haploview: analysis and visualization of LD and haplotype maps

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Statistics notes. The odds ratio

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The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response.

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Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakistani patients

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Lack of association between DRD3 gene polymorphism and response to clozapine in Turkish schizoprenia patients.

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Neuroleptics Reduce Spinal Fluid Cyclic AMP in Schizophrenic Patients

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S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functio

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Plasma levels of interleukin-6 and tumor necrosis factor alpha in chronic schizophrenia: effects of clozapine treatment.

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Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells

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A cluster of single nucleotide polymorphisms in the 5'-leader of the human dopamine D3 receptor gene (DRD3) and its relationship to schizophrenia.

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A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other

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Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

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Novel, Replicated Associations Between Dopamine D3 Receptor Gene Polymorphisms and Schizophrenia in Two Independent Samples

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10.1038/TPJ.2009.65

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Europe PubMed Central

15 September 2017

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