(Q39925886)

English

Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo

scientific article published on 24 October 2008

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

15 September 2017

Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo (English)

1 reference

Europe PubMed Central

15 September 2017

pancreatic cancer

1 reference

based on heuristic

inferred from title

author name string

X H Shi

1

1 reference

Europe PubMed Central

15 September 2017

Z Y Liang

2

1 reference

Europe PubMed Central

15 September 2017

X Y Ren

3

1 reference

Europe PubMed Central

15 September 2017

T H Liu

4

1 reference

Europe PubMed Central

15 September 2017

publication date

24 October 2008

1 reference

Europe PubMed Central

15 September 2017

Cancer Gene Therapy

1 reference

Europe PubMed Central

15 September 2017

16

1 reference

Europe PubMed Central

15 September 2017

227-236

1 reference

Europe PubMed Central

15 September 2017

3

1 reference

Europe PubMed Central

15 September 2017

https://scigraph.springernature.com/pub.10.1038/cgt.2008.82

0 references

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Development of gene therapy to target pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Mechanisms of disease: PI3K/AKT signaling in gastrointestinal cancers

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Antisense oligodeoxynucleotides for urokinase-plasminogen activator receptor have anti-invasive and anti-proliferative effects in vitro and inhibit spontaneous metastases of human melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

mTOR-targeted therapy of cancer with rapamycin derivatives

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Molecular aspects of pancreatic cancer and future perspectives

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Combined inhibition of the phosphatidylinositol 3-kinase/Akt and Ras/mitogen-activated protein kinase pathways results in synergistic effects in glioblastoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Phosphorylation by Glycogen Synthase Kinase-3 Controls c-Myc Proteolysis and Subnuclear Localization

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

21 January 2018

Cancer statistics, 2001

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular-targeted agents in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

The functions of Myc in cell cycle progression and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: incidence, mechanisms, and clinical significance

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

The amino-terminal fragment of human urokinase directs a recombinant chimeric toxin to target cells: internalization is toxin mediated.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2008.82

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CGT.2008.82

1 reference

Europe PubMed Central

15 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

15 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39925886&oldid=1878697323"