(Q39943795)

English

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition

scientific article published on 3 September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

8

object named as

Shibo Jiang

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Europe PubMed Central

PMC publication ID

15 September 2017

7

object named as

Asim K Debnath

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

author name string

Yuxian He

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Shuwen Liu

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Jingjing Li

3

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Hong Lu

4

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Zhi Qi

5

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Zhonghua Liu

6

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

language of work or name

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publication date

3 September 2008

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Europe PubMed Central

PMC publication ID

15 September 2017

number of pages

11

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inferred from page(s)

Journal of Virology

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Europe PubMed Central

PMC publication ID

15 September 2017

82

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Europe PubMed Central

PMC publication ID

15 September 2017

22

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

11129-11139

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Identification of a critical motif for the human immunodeficiency virus type 1 (HIV-1) gp41 core structure: implications for designing novel anti-HIV fusion inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: implications for therapy and vaccine development

1 reference

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22 September 2017

HIV entry inhibitors.

1 reference

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AIDS virus envelope spike structure

1 reference

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22 September 2017

HIV entry inhibitors targeting gp41: from polypeptides to small-molecule compounds

1 reference

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22 September 2017

Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended

1 reference

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22 September 2017

Progress in identifying peptides and small-molecule inhibitors targeted to gp41 of HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection

1 reference

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22 September 2017

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation

1 reference

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22 September 2017

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

1 reference

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22 September 2017

HIV-1 gp41: mediator of fusion and target for inhibition

1 reference

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22 September 2017

The HIV Env-mediated fusion reaction

1 reference

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22 September 2017

The structural biology of type I viral membrane fusion

1 reference

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A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

1 reference

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22 September 2017

Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America

1 reference

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22 September 2017

Genetic evidence that interhelical packing interactions in the gp41 core are critical for transition of the human immunodeficiency virus type 1 envelope glycoprotein to the fusion-active state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Structural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Mechanisms of viral membrane fusion and its inhibition

1 reference

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22 September 2017

Protein design of an HIV-1 entry inhibitor

1 reference

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22 September 2017

An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Structure-function studies of the self-assembly domain of the human immunodeficiency virus type 1 transmembrane protein gp41.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Interactions between HIV-1 gp41 core and detergents and their implications for membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Inhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

A conformation-specific monoclonal antibody reacting with fusion-active gp41 from the human immunodeficiency virus type 1 envelope glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Mutational analysis of residues in the coiled-coil domain of human immunodeficiency virus type 1 transmembrane protein gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides

1 reference

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HIV entry and its inhibition

1 reference

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22 September 2017

Mutations in the leucine zipper-like heptad repeat sequence of human immunodeficiency virus type 1 gp41 dominantly interfere with wild-type virus infectivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Capture of an early fusion-active conformation of HIV-1 gp41

1 reference

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

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Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides.

1 reference

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22 September 2017

Atomic structure of a thermostable subdomain of HIV-1 gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Atomic structure of the ectodomain from HIV-1 gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Core structure of gp41 from the HIV envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Mutational analysis of the leucine zipper-like motif of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

1 reference

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22 September 2017

Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus env proteins possess a functionally conserved assembly domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization

1 reference

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22 September 2017

Enhancement of human immunodeficiency virus type 1 infection by antisera to peptides from the envelope glycoproteins gp120/gp41

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

22 September 2017

Surface salt bridges stabilize the GCN4 leucine zipper

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

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HIV-1 inhibition by a peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

17 June 2018

A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

17 June 2018

Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

17 June 2018

Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

17 June 2018

Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Conserved residue Lys574 in the cavity of HIV-1 Gp41 coiled-coil domain is critical for six-helix bundle stability and virus entry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Structurally altered peptides reveal an important role for N-terminal heptad repeat binding and stability in the inhibitory action of HIV-1 peptide DP178.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Remodeling of gp41-C34 peptide leads to highly effective inhibitors of the fusion of HIV-1 with target cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Buried polar interactions and conformational stability in the simian immunodeficiency virus (SIV) gp41 core

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573276

20 August 2018

Analysis of the immunogenic properties of a single-chain polypeptide analogue of the HIV-1 gp120?CD4 complex in transgenic mice that produce human immunoglobulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How Structure Correlates to Function for Membrane Associated HIV-1 gp41 Constructs Corresponding to the N-terminal Half of the Ectodomain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the HIV-1 gp41 fusogenic core conformation modeled by synthetic peptides: applicable for identification of HIV-1 fusion inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV gp41 C-terminal heptad repeat contains multifunctional domains. Relation to mechanisms of action of anti-HIV peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the HIV N-terminal fusion peptide-containing region in context of key gp41 fusion conformations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstrating the C-terminal boundary of the HIV 1 fusion conformation in a dynamic ongoing fusion process and implication for fusion inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/18768964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01060-08

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

release_glp3hu3f2nemdbhvfc4kaa4caa

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https://api.fatcat.wiki/v0/release/glp3hu3f2nemdbhvfc4kaa4caa

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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