(Q39956628)

15 September 2017

title

Assembly, purification, and assay of the activity of the ASC pyroptosome (English)

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15 September 2017

author name string

Teresa Fernandes-Alnemri

series ordinal

1

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15 September 2017

Emad S Alnemri

series ordinal

2

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15 September 2017

language of work or name

English

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publication date

1 January 2008

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15 September 2017

published in

Methods in Enzymology

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15 September 2017

volume

442

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15 September 2017

page(s)

251-270

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

15 September 2017

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

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Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome

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Cryopyrin activates the inflammasome in response to toxins and ATP

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7 January 2021

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

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7 January 2021

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

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7 January 2021

Autophagy and inflammatory cell death, partners of innate immunity

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7 January 2021

CATERPILLERs, pyrin and hereditary immunological disorders

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7 January 2021

Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme

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7 January 2021

Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants

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7 January 2021

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

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7 January 2021

10.1016/S0076-6879(08)01413-4

Identifiers

DOI

1 reference

15 September 2017

1 reference