(Q39970436)

16 September 2017

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer (English)

1 reference

16 September 2017

1 reference

2

1 reference

16 September 2017

3

1 reference

16 September 2017

Denzil Bernard

11

0 references

Thomas E. Carey

object named as

Thomas E Carey

13

0 references

author name string

Sanjeev Shangary

1

1 reference

16 September 2017

Su Qiu

4

1 reference

16 September 2017

Zaneta Nikolovska-Coleska

5

1 reference

16 September 2017

Joshua A Bauer

6

1 reference

16 September 2017

Meilan Liu

7

1 reference

16 September 2017

Guoping Wang

8

1 reference

16 September 2017

Yipin Lu

9

1 reference

16 September 2017

Donna McEachern

10

1 reference

16 September 2017

Carol R Bradford

12

1 reference

16 September 2017

Shaomeng Wang

14

1 reference

16 September 2017

1 June 2008

1 reference

Molecular Cancer Therapeutics

16 September 2017

1 reference

16 September 2017

7

1 reference

16 September 2017

6

1 reference

16 September 2017

1533-1542

1 reference

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

16 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Wild-type p53: tumors can't stand it.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

MDM2 inhibitors for cancer therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Mutational spectrum of p53 mutations in primary breast and ovarian tumors.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Mechanisms of p53-dependent apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

22 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

p53 and human cancer: the first ten thousand mutations.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

22 September 2017

Mdm2: the ups and downs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Functions of the MDM2 oncoprotein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

p53, the cellular gatekeeper for growth and division

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

The p53-mdm-2 autoregulatory feedback loop

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Mapping of the p53 and mdm-2 interaction domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Inactivation of the p53 pathway in retinoblastoma.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Structure-based design of potent non-peptide MDM2 inhibitors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

Stable suppression of tumorigenicity by virus-mediated RNA interference

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494594

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18566224

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18566224

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-08-0140

1 reference

release_rphu2olmwjf2nkw224a4ex3x3y

16 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rphu2olmwjf2nkw224a4ex3x3y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

16 September 2017

PubMed publication ID

18566224

1 reference