(Q39975225)

English

Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.

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1 reference

Europe PubMed Central

16 September 2017

retracted paper

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Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK. (English)

1 reference

Europe PubMed Central

16 September 2017

apoptotic process

0 references

1 reference

based on heuristic

inferred from title

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Yi-He Ling

1

1 reference

Europe PubMed Central

16 September 2017

Ruoping Lin

2

1 reference

Europe PubMed Central

16 September 2017

Roman Perez-Soler

3

1 reference

Europe PubMed Central

16 September 2017

publication date

4 June 2008

1 reference

Europe PubMed Central

16 September 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

16 September 2017

74

1 reference

Europe PubMed Central

16 September 2017

3

1 reference

Europe PubMed Central

16 September 2017

793-806

1 reference

Europe PubMed Central

16 September 2017

Role of Bax and Bak in mitochondrial morphogenesis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

BH3-Only proteins-essential initiators of apoptotic cell death

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Mitochondria as the central control point of apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

59 Inhibitors of the ATP synthetase systems

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Epidermal growth factor binding, stimulation of phosphorylation, and inhibition of gluconeogenesis in rat proximal tubule

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Life-or-death decisions by the Bcl-2 protein family.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Erlotinib in previously treated non-small-cell lung cancer

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lin

2 references

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1124/MOL.107.034827

Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Growth factor receptor tyrosine kinases

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Induction of apoptosis by cancer chemotherapy.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Untangling the ErbB signalling network

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Apoptosis-based therapies

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

The biochemistry of programmed cell death

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: role as anticancer agents

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Structure of Bax: coregulation of dimer formation and intracellular localization

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1124/MOL.107.044396

Identifiers

10.1124/MOL.107.044396

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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