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The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway
scientific article published on 01 June 2001
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
title
The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
monoclonal antibody
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inferred from title
author
Bolin Liu
series ordinal
1
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
Fan Z
series ordinal
2
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stated in
Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
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9 November 2019
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English
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publication date
1 June 2001
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
20
1 reference
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
28
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
3726-3734
1 reference
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Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1204490
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Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis
1 reference
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Death receptors: signaling and modulation
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reference URL
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7 January 2021
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Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway
1 reference
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Autocrine regulation of membrane transforming growth factor-alpha cleavage
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Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
1 reference
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7 January 2021
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Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.
1 reference
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Crossref
reference URL
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7 January 2021
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The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.
1 reference
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Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.
1 reference
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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
1 reference
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A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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inferred from DOI database lookup
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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inferred from DOI database lookup
Therapeutic application of anti-growth factor receptor antibodies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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Modulation of resistance to anti-APO-1-induced apoptosis in osteosarcoma cells by cytokines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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inferred from DOI database lookup
The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
1 reference
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Crossref
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7 January 2021
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Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
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7 January 2021
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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis
1 reference
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Crossref
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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
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Crossref
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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
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reference URL
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Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells
1 reference
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Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
1 reference
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Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c-jun N-terminal kinase activity
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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
1 reference
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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
1 reference
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Crossref
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Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.
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Crossref
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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
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An induced proximity model for caspase-8 activation.
1 reference
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Crossref
reference URL
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7 January 2021
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Apoptosis by death factor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: killer proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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inferred from DOI database lookup
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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7 January 2021
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Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
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7 January 2021
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inferred from DOI database lookup
CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
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The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death
1 reference
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Crossref
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7 January 2021
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Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle.
1 reference
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7 January 2021
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Pro-caspase-3 is a major physiologic target of caspase-8.
1 reference
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Crossref
reference URL
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7 January 2021
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Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
1 reference
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Crossref
reference URL
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Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.
1 reference
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Crossref
reference URL
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7 January 2021
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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
1 reference
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reference URL
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7 January 2021
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Caspases: enemies within
1 reference
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reference URL
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7 January 2021
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Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Autoproteolytic activation of pro-caspases by oligomerization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1204490
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1204490
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Dimensions Publication ID
1041559094
0 references
PubMed publication ID
11439335
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11439335
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11439335%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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