(Q39985185)

16 September 2017

title

Specific cysteines in beta3 are involved in disulfide bond exchange-dependent and -independent activation of alphaIIbbeta3. (English)

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16 September 2017

Meytal Landau

3

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Uri Seligsohn

series ordinal

5

object named as

Uri Seligsohn

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16 September 2017

Ronit Mor-Cohen

1

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16 September 2017

Nurit Rosenberg

series ordinal

2

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16 September 2017

Judith Lahav

series ordinal

4

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16 September 2017

language of work or name

English

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publication date

5 May 2008

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Journal of Biological Chemistry

16 September 2017

published in

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16 September 2017

volume

283

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16 September 2017

issue

28

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16 September 2017

page(s)

19235-19244

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Integrins: bidirectional, allosteric signaling machines

16 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802399200

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21 January 2018

1 reference

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Platelet integrin GPIIb/IIIa: structure-function correlations. An update and lessons from other integrins

21 January 2018

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Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.

21 January 2018

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

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Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

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Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

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The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

21 January 2018

1 reference

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A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype

21 January 2018

1 reference

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Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation

21 January 2018

1 reference

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Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit

21 January 2018

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Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family

21 January 2018

1 reference

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A redox site involved in integrin activation

21 January 2018

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Mechanism of integrin activation by disulfide bond reduction

21 January 2018

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Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange

21 January 2018

1 reference

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The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase activity.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

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Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

21 January 2018

1 reference

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Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits

21 January 2018

1 reference

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Disruption of the beta3 663-687 disulfide bridge confers constitutive activity to beta3 integrins

21 January 2018

1 reference

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Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

21 January 2018

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Structure and function of epidermal growth factor-like regions in proteins

21 January 2018

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Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex

21 January 2018

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Allosteric disulfide bonds in thrombosis and thrombolysis.

21 January 2018

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Bacitracin reveals a role for multiple thiol isomerases in platelet function

21 January 2018

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Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation

21 January 2018

1 reference

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Integrin structure: new twists and turns in dynamic cell adhesion

21 January 2018

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Nanostructure of fibrillin-1 reveals compact conformation of EGF arrays and mechanism for extensibility.

21 January 2018

1 reference

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Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation

21 January 2018

1 reference

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Three Novel Integrin β3 Subunit Missense Mutations (H280P, C560F, and G579S) in Thrombasthenia, Including One (H280P) Prevalent in Japanese Patients

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M802399200

1 reference

16 September 2017

1 reference