(Q39985730)

16 September 2017

title

Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli (English)

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16 September 2017

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A P Kouzmenko

1

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16 September 2017

K Takeyama

2

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16 September 2017

Y Kawasaki

3

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16 September 2017

T Akiyama

4

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16 September 2017

S Kato

5

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16 September 2017

language of work or name

English

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publication date

5 May 2008

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16 September 2017

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16 September 2017

volume

27

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16 September 2017

issue

36

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16 September 2017

page(s)

4888-4899

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APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export

16 September 2017

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Age at exposure and Apc status influence the levels of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in mouse intestine and liver

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H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

31 March 2020

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The APC protein binds to A/T rich DNA sequences

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31 March 2020

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Nuclear accumulation of full-length and truncated adenomatous polyposis coli protein in tumor cells depends on proliferation

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Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion.

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APC, signal transduction and genetic instability in colorectal cancer

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MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer

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Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

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Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers

31 March 2020

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Loss of adenomatous polyposis coli gene function disrupts thymic development

31 March 2020

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Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC

31 March 2020

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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

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Identification of a link between the tumour suppressor APC and the kinesin superfamily

31 March 2020

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Dimer formation by an N-terminal coiled coil in the APC protein

31 March 2020

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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

31 March 2020

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Asef, a link between the tumor suppressor APC and G-protein signaling

31 March 2020

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Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

31 March 2020

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Mutated APC and Asef are involved in the migration of colorectal tumour cells

31 March 2020

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The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome

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Wnt/beta-catenin and estrogen signaling converge in vivo

31 March 2020

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Ligand-dependent interaction between estrogen receptor alpha and adenomatous polyposis coli.

31 March 2020

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Histone acetyltransferase complexes: one size doesn't fit all

31 March 2020

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Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

31 March 2020

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Id2 gene-targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Orchestration of chromatin-based processes: mind the TRRAP.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Modulation of oestrogen receptor signalling by association with the activated dioxin receptor

31 March 2020

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Altering nucleosomes during DNA double-strand break repair in yeast.

31 March 2020

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Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

31 March 2020

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Topoisomerase I inhibitors: camptothecins and beyond

31 March 2020

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APC mutations occur early during colorectal tumorigenesis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.127

The APC tumour suppressor has a nuclear export function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.127

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.127

Tip60 in DNA damage response and growth control: many tricks in one HAT.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

The histone code at DNA breaks: a guide to repair?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.127

1 reference

16 September 2017

1 reference