(Q39990800)

16 September 2017

title

Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays (English)

1 reference

16 September 2017

1 reference

Rosalie K Elespuru

1

1 reference

16 September 2017

Rajiv Agarwal

2

1 reference

16 September 2017

Aisar H Atrakchi

3

1 reference

16 September 2017

C Anita H Bigger

4

1 reference

16 September 2017

Robert H Heflich

5

1 reference

16 September 2017

Devaraya R Jagannath

6

1 reference

16 September 2017

Dan D Levy

7

1 reference

16 September 2017

Martha M Moore

8

1 reference

16 September 2017

Yanli Ouyang

9

1 reference

16 September 2017

Timothy W Robison

10

1 reference

16 September 2017

Rene E Sotomayor

11

1 reference

16 September 2017

Michael C Cimino

12

1 reference

16 September 2017

Kerry L Dearfield

13

1 reference

16 September 2017

publication date

31 March 2009

1 reference

16 September 2017

published in

Toxicological Sciences

1 reference

16 September 2017

volume

109

1 reference

16 September 2017

issue

2

1 reference

16 September 2017

page(s)

172-179

1 reference

Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

16 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Gene expression profile analysis: an emerging approach to investigate mechanisms of genotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mutagenicity test schemes and guidelines: U.S. EPA Office of Pollution Prevention and Toxics and Office of Pesticide Programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Toxicology. Transforming environmental health protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mutagenicity of nitrosocarbaryl and other methylating nitrosamides as related to uptake in haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mutagenic potency of food-derived heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Predicting rodent carcinogenicity from mutagenic potency measured in the Ames Salmonella assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Extended quantitative structure-activity relationships for 80 aromatic and heterocyclic amines: structural, electronic, and hydropathic factors affecting mutagenic potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation part IV: a strategy in genotoxicity testing in drug development: some examples

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation. Part II: Performances of the in vitro micronucleus test compared to the mouse lymphoma assay and the in vitro chromosome aberration assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genotoxic effects of acrylamide and glycidamide in mouse lymphoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-cells from the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mouse lymphoma thymidine kinase gene mutation assay: follow-up meeting of the International Workshop on Genotoxicity Testing--Aberdeen, Scotland, 2003--Assay acceptance criteria, positive controls, and data evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mouse Lymphoma Thymidine Kinase Gene Mutation Assay: International Workshop on Genotoxicity Tests Workgroup Report—Plymouth, UK 2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Mouse lymphoma thymidine kinase gene mutation assay: follow-up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Measuring the mitotic index in chemically-treated human lymphocyte cultures by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Improving dose selection and identification of aneugens in the in vitro chromosome aberration test by integration of flow cytometry-based methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

ICH-harmonised guidances on genotoxicity testing of pharmaceuticals: evolution, reasoning and impact.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation part IV: Recommendation of a working group of the Gesellschaft fuer Umwelt-Mutationsforschung (GUM) for a simple and straightforward approach to genotoxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Erythrocyte-based Pig-a gene mutation assay: demonstration of cross-species potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation part VI: when salt and sugar and vegetables are positive, how can genotoxicity data serve to inform risk assessment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Comparison of carcinogenic and in vivo genotoxic potency estimates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicology: current status of methods of carcinogen identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Relevance and follow-up of positive results in in vitro genetic toxicity assays: an ILSI-HESI initiative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

Genetic toxicity assessment: employing the best science for human safety evaluation part III: the comet assay as an alternative to in vitro clastogenicity tests for early drug candidate selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP067

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFP067

1 reference

16 September 2017

1 reference