(Q39995055)

16 September 2017

title

Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis (English)

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16 September 2017

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7

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Kurt R. Zinn

6

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Gene P. Siegal

4

object named as

Gene P Siegal

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16 September 2017

Diptiman Chanda

1

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16 September 2017

Tatyana Isayeva

2

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16 September 2017

Sanjay Kumar

3

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16 September 2017

April A Szafran

5

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16 September 2017

Selvarangan Ponnazhagan

8

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16 September 2017

publication date

18 March 2008

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16 September 2017

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16 September 2017

volume

16

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16 September 2017

issue

5

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16 September 2017

page(s)

871-878

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16 September 2017

cites work

Cancer statistics, 2007

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy

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https://api.crossref.org/works/10.1038%2FMT.2008.48

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Mechanisms of bone metastasis

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Mechanisms of disease: roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis.

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

The RANK/RANKL/OPG triad in cancer-induced bone diseases

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Key roles of the OPG-RANK-RANKL system in bone oncology

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Regulation of cancer cell migration and bone metastasis by RANKL.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Role of osteoprotegerin (OPG) in cancer

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude mice.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Adeno-associated virus vectors: potential applications for cancer gene therapy

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival?

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Adeno-associated virus-mediated osteoprotegerin gene transfer protects against particulate polyethylene-induced osteolysis in a murine model

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Gene therapy with human osteoprotegerin decreases callus remodeling with limited effects on biomechanical properties

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Osteoprotegerin in prostate cancer bone metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption

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https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

The bone microenvironment in metastasis; what is special about bone?

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

A helper virus-free packaging system for recombinant adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Lack of site-specific integration of the recombinant adeno-associated virus 2 genomes in human cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.48

7 January 2021

Identifiers

DOI

10.1038/MT.2008.48

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16 September 2017

1 reference