(Q39997013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

0 references

0 references

8

1 reference

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4 January 2020

Marisol Soengas

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Thomas E. Carey

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Matthew J Sikora

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Joshua A Bauer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Monique Verhaegen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Thomas J Belbin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Michael B Prystowsky

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Joseph C Taylor

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

J Chad Brenner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Carol R Bradford

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

publication date

20 May 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

Cancer Biology and Therapy

4 January 2020

published in

1 reference

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4 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

767-776

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4157391/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Targeting apoptosis to overcome cisplatin resistance: a translational study in head and neck cancer

1 reference

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Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours

22 September 2017

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Redox stress and the contributions of BH3-only proteins to infarction.

22 September 2017

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(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo

22 September 2017

1 reference

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The antioxidant function of the p53 tumor suppressor

22 September 2017

1 reference

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Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth

22 September 2017

1 reference

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In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.

22 September 2017

1 reference

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Mechanism of Drug and Toxic Actions of Gossypol: Focus on Reactive Oxygen Species and Electron Transfer

22 September 2017

1 reference

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Redox proteins in mammalian cell death: an evolutionarily conserved function in mitochondria and prokaryotes

22 September 2017

1 reference

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Apoptosis: a link between cancer genetics and chemotherapy

22 September 2017

1 reference

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Predictive factors in head and neck cancer

22 September 2017

1 reference

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Gossypol treatment of recurrent adult malignant gliomas

22 September 2017

1 reference

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BCL-2 family: regulators of cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157391

Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells

22 September 2017

1 reference

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Oral gossypol in the treatment of metastatic adrenal cancer

22 September 2017

1 reference

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Bcl-XL and Bcl-2 repress a common pathway of cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157391

Probing into the mechanism of action, metabolism and toxicity of gossypol by studying its (+)- and (-)-stereoisomers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157391

Physiological effects and metabolism of gossypol

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157391

Novel effects of gossypol, a chemical contraceptive in man: mobilization of internal Ca(2+) and activation of external Ca(2+) entry in intact cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157391

Programmed cell death: Bcl-2.

25 September 2017

1 reference

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Inhibition of human prostate cancer cells growth by gossypol is associated with stimulation of transforming growth factor-beta

25 September 2017

1 reference

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Synergistic interaction between cisplatin and tamoxifen delays the emergence of cisplatin resistance in head and neck cancer cell lines

25 September 2017

1 reference

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Bcl-2/adenovirus E1B 19 kDa interacting protein-3 knockdown enables growth of breast cancer metastases in the lung, liver, and bone

25 September 2017

1 reference

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Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation

17 June 2018

1 reference

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Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.

17 June 2018

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Antibodies to human squamous cell carcinoma

17 June 2018

1 reference

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Immortalization of normal human oral keratinocytes with type 16 human papillomavirus

17 June 2018

1 reference

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Airing out an antioxidant role for the tumor suppressor p53.

17 June 2018

1 reference

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Single-cycle induction chemotherapy selects patients with advanced laryngeal cancer for combined chemoradiation: a new treatment paradigm

20 August 2018

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Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

20 August 2018

1 reference

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A patient-tailored N-acetylcysteine protocol for acute acetaminophen intoxication

20 August 2018

1 reference

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Production of reactive oxygen species and loss of viability in yeast mitochondrial mutants: protective effect of Bcl-xL.

20 August 2018

1 reference

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Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosis

20 August 2018

1 reference

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Protective effects of melatonin, vitamin E and N-acetylcysteine against acetaminophen toxicity in mice: a comparative study

20 August 2018

1 reference

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Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.

20 August 2018

1 reference

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Efficacy of oral versus intravenous N-acetylcysteine in acetaminophen overdose: results of an open-label, clinical trial.

20 August 2018

1 reference

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Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.

20 August 2018

1 reference

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Hypoxia induces the expression of the pro-apoptotic gene BNIP3

20 August 2018

1 reference

12 December 2020

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells

1 reference

12 December 2020

Human Squamous Cell Carcinoma: Establishment and Characterization of New Permanent Cell Lines

1 reference

12 December 2020

Oxygen radical formation induced by gossypol in rat liver microsomes and human sperm

1 reference

12 December 2020

A preliminary clinical study of gossypol in advanced human cancer

1 reference

12 December 2020

Late-presenting acute acetaminophen toxicity and the role of N-acetylcysteine

1 reference

12 December 2020

BCL-2 gene family and the regulation of programmed cell death

1 reference

12 December 2020

Molecular profiling of tumor progression in head and neck cancer

1 reference

12 December 2020

Gossypol arrests human benign prostatic hyperplastic cell growth at G0/G1 phase of the cell cycle

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.7.5.5767

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18376141%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18376141

1 reference