(Q40018639)

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Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

scientific article published on 5 February 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

16 September 2017

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma (English)

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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Ignacio I Wistuba

13

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Ignacio I Wistuba

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Europe PubMed Central

16 September 2017

PMC publication ID

14

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John V Heymach

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16 September 2017

Vassiliki Papadimitrakopoulou

9

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Vassiliki A Papadimitrakopoulou

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Europe PubMed Central

PMC publication ID

16 September 2017

12

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Patrick Hwu

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Europe PubMed Central

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16 September 2017

author name string

Yanyan Lou

1

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16 September 2017

Lixia Diao

2

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16 September 2017

Edwin Roger Parra Cuentas

3

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16 September 2017

Warren L Denning

4

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16 September 2017

Limo Chen

5

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16 September 2017

You Hong Fan

6

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16 September 2017

Lauren A Byers

7

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16 September 2017

Jing Wang

8

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16 September 2017

Carmen Behrens

10

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16 September 2017

Jaime Canales Rodriguez

11

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16 September 2017

Don L Gibbons

15

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16 September 2017

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publication date

5 February 2016

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16 September 2017

Clinical Cancer Research

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16 September 2017

22

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16 September 2017

14

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Europe PubMed Central

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16 September 2017

3630-3642

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Europe PubMed Central

PMC publication ID

16 September 2017

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

1 reference

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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

1 reference

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Programmed death ligand-1 expression in non-small cell lung cancer

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Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy

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An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

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The BATTLE trial: personalizing therapy for lung cancer

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Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.

1 reference

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22 September 2017

Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape

1 reference

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22 September 2017

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

1 reference

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22 September 2017

A perspective on cancer cell metastasis

1 reference

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Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment

1 reference

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22 September 2017

Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence

1 reference

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22 September 2017

Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy

1 reference

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Epithelial-mesenchymal transitions in development and disease

1 reference

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Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma

1 reference

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Epithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lung

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

1 reference

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Immune suppression in the tumor microenvironment

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Epithelial-Mesenchymal Transition

1 reference

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2 December 2018

Identifiers

10.1158/1078-0432.CCR-15-1434

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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