(Q40020065)

16 September 2017

title

Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors (English)

1 reference

16 September 2017

D Miyamoto

1

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16 September 2017

M Miyamoto

2

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16 September 2017

A Takahashi

3

1 reference

16 September 2017

Y Yomogita

4

1 reference

16 September 2017

H Higashi

5

1 reference

16 September 2017

S Kondo

6

1 reference

16 September 2017

M Hatakeyama

7

1 reference

16 September 2017

language of work or name

English

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publication date

28 January 2008

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16 September 2017

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16 September 2017

volume

27

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16 September 2017

issue

25

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16 September 2017

page(s)

3508-3515

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Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates

16 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Structural and evolutionary relationships among protein tyrosine phosphatase domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Germline mutations in HRAS proto-oncogene cause Costello syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

A role for the scaffolding adapter GAB2 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Juvenile myelomonocytic leukemia and Noonan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Oncogenic mechanisms of the Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Crystal structure of the tyrosine phosphatase SHP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

PTPN11 (Protein-Tyrosine Phosphatase, Nonreceptor-Type 11) Mutations in Seven Japanese Patients with Noonan Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Inherited predispositions and hyperactive Ras in myeloid leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

The role of Shp2 (PTPN11) in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Germline gain-of-function mutations in SOS1 cause Noonan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Germline KRAS mutations cause Noonan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Mechanism of activation of a human oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

Prevalence of priapism in children and adolescents with sickle cell anemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

inferred from DOI database lookup

7 January 2021

based on heuristic

PTPN11 (protein-tyrosine phosphatase, nonreceptor-type 11) mutations in seven Japanese patients with Noonan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

inferred from DOI database lookup

7 January 2021

based on heuristic

Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211019

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1211019

1 reference

Dimensions Publication ID

16 September 2017

1016134323

0 references

1 reference