(Q40039619)

English

N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity

scientific article published on 5 December 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

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object named as

Marc G Caron

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Europe PubMed Central

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16 September 2017

author name string

Niels H Jensen

1

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Europe PubMed Central

PubMed publication ID

16 September 2017

Ramona M Rodriguiz

2

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Europe PubMed Central

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16 September 2017

William C Wetsel

4

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16 September 2017

Richard B Rothman

5

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16 September 2017

Bryan L Roth

6

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16 September 2017

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publication date

5 December 2007

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Europe PubMed Central

PubMed publication ID

16 September 2017

Neuropsychopharmacology

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Europe PubMed Central

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16 September 2017

33

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16 September 2017

10

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16 September 2017

2303-2312

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Europe PubMed Central

PubMed publication ID

16 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.npp.1301646

0 references

Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

1 reference

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Characterization of 5-HT1A receptor-mediated [35S]GTPgammaS binding in rat hippocampal membranes

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Mining the receptorome

1 reference

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Quetiapine poisoning: a case series

1 reference

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An integrated in silico 3D model-driven discovery of a novel, potent, and selective amidosulfonamide 5-HT1A agonist (PRX-00023) for the treatment of anxiety and depression

1 reference

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A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression

1 reference

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7 January 2021

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The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice

1 reference

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The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions?

1 reference

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Analysis and pharmacokinetics of quetiapine and two metabolites in human plasma using reversed-phase HPLC with ultraviolet and electrochemical detection

1 reference

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Clinical pharmacokinetics of quetiapine: an atypical antipsychotic

1 reference

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7 January 2021

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Hippocampal neurogenesis: regulation by stress and antidepressants

1 reference

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7 January 2021

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Vmat2 heterozygous mutant mice display a depressive-like phenotype.

1 reference

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Time course of central nervous dopamine-D2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel) in patients with schizophrenia

1 reference

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Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics

1 reference

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Quetiapine : A Review of its Use in Schizophrenia

1 reference

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Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression.

1 reference

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Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia

1 reference

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From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase

1 reference

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7 January 2021

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H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.

1 reference

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7 January 2021

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Clinical pharmacokinetics of atypical antipsychotics: a critical review of the relationship between plasma concentrations and clinical response

1 reference

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7 January 2021

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Serotonin receptors: their key role in drugs to treat schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301646

7 January 2021

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Quetiapine prevents anhedonia induced by acute or chronic stress

1 reference

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7 January 2021

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Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat1 gene

1 reference

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7 January 2021

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Cyclic antidepressants and the risk of sudden cardiac death

1 reference

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QT prolongation through hERG K(+) channel blockade: current knowledge and strategies for the early prediction during drug development

1 reference

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Drugs and valvular heart disease

1 reference

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7 January 2021

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Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

1 reference

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7 January 2021

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Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

1 reference

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7 January 2021

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Effectiveness of adjunctive antidepressant treatment for bipolar depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301646

7 January 2021

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Why mice are neither miniature humans nor small rats: a cautionary tale involving 5-hydroxytryptamine-6 serotonin receptor species variants

1 reference

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7 January 2021

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Research on adverse drug events. I. Muscarinic M3 receptor binding affinity could predict the risk of antipsychotics to induce type 2 diabetes

1 reference

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7 January 2021

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Development and evaluation of an in silico model for hERG binding.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301646

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening the receptorome: an efficient approach for drug discovery and target validation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of quetiapine monotherapy in bipolar I and II depression: a double-blind, placebo-controlled study (the BOLDER II study).

1 reference

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Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression

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Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

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Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice

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Identifiers

10.1038/SJ.NPP.1301646

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

ResearchGate publication ID

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