(Q40046039)

English

Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade

scientific article published on 21 November 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

1 reference

based on heuristic

inferred from title

object named as

Marina Marini

3

0 references

object named as

Stefan Laufer

9

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object named as

Carla Ferreri

4

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author name string

Simona Tavolari

1

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Massimiliano Bonafè

2

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Giovanna Bartolini

5

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Elisa Brighenti

6

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Sonia Manara

7

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Vittorio Tomasi

8

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Tiziana Guarnieri

10

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

language of work or name

0 references

publication date

21 November 2007

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

29

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

371-380

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

Stories about acyl chains

1 reference

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21 January 2018

Phospholipase A2 enzymes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Roles of prostanoids in colon carcinogenesis and their potential targeting for cancer chemoprevention.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Intracellular unesterified arachidonic acid signals apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Expression of 5-lipoxygenase in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Dual acting anti-inflammatory drugs.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Combined lipoxygenase/cyclo-oxygenase inhibition in the elderly: the example of licofelone

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Superiority of the gastroduodenal safety profile of licofelone over rofecoxib, a COX-2 selective inhibitor, in dogs

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Selected polychlorobiphenyls congeners bind to estrogen receptor alpha in human umbilical vascular endothelial (HUVE) cells modulating angiogenesis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Trans lipid formation induced by thiols in human monocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

The effect of leukotrienes B and selected HETEs on the proliferation of colon cancer cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Enhancement of colon carcinogenesis by prostaglandin E2 administration

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Phospholipase A(2) regulation of arachidonic acid mobilization

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Phospholipase A2 as targets for anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Oxalate inhibits renal proximal tubule cell proliferation via oxidative stress, p38 MAPK/JNK, and cPLA2 signaling pathways

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Apoptosis as a prognostic factor in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

NSAIDs and cancer prevention: targets downstream of COX-2.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

NSAIDs and chemoprevention

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Cleavage of Bax-alpha and Bcl-x(L) during carboplatin-mediated apoptosis in squamous cell carcinoma cell line

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Cleavage of Bax enhances its cell death function

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Structure of Bax: coregulation of dimer formation and intracellular localization

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Inhibition of angiogenesis by non-steroidal anti-inflammatory drugs: from the bench to the bedside and back

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGM265

21 January 2018

Identifiers

10.1093/CARCIN/BGM265

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

ResearchGate publication ID

0 references

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