(Q40052972)

16 September 2017

Modulation of the eukaryotic initiation factor 2 alpha-subunit kinase PERK by tyrosine phosphorylation (English)

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16 September 2017

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6

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16 September 2017

Heather P Harding

5

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author name string

Qiaozhu Su

1

1 reference

16 September 2017

Shuo Wang

2

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16 September 2017

Hong Qing Gao

3

1 reference

16 September 2017

Shirin Kazemi

4

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16 September 2017

Antonis E Koromilas

7

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16 September 2017

language of work or name

English

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publication date

12 November 2007

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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16 September 2017

469-475

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16 September 2017

1

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Translation factors: in sickness and in health

16 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Does the ribosome translate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Translational control in stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Molecular mechanisms of translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Gene-specific regulation by general translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

eIF2 and the control of cell physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

The double-stranded RNA-dependent protein kinase PKR: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Functional characterization of pkr gene products expressed in cells from mice with a targeted deletion of the N terminus or C terminus domain of PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

The T-cell protein tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704612200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704612200

1 reference

16 September 2017

1 reference