(Q40066258)

17 September 2017

title

Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan (English)

1 reference

17 September 2017

Murugesan K Gounder

1

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17 September 2017

Ahamed S Nazar

2

1 reference

17 September 2017

Ahamed Saleem

3

1 reference

17 September 2017

Pooja Pungaliya

4

1 reference

17 September 2017

Diptee Kulkarni

5

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17 September 2017

Richard Versace

6

1 reference

17 September 2017

Eric H Rubin

7

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17 September 2017

publication date

18 October 2007

1 reference

Investigational New Drugs

17 September 2017

published in

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17 September 2017

volume

26

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17 September 2017

issue

3

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17 September 2017

page(s)

205-213

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https://scigraph.springernature.com/pub.10.1007/s10637-007-9093-0

17 September 2017

exact match

0 references

cites work

Yeast as a model organism for studying the actions of DNA topoisomerase-targeted drugs

1 reference

https://api.crossref.org/works/10.1007%2FS10637-007-9093-0

No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-007-9093-0

Gene mutation analysis and quantitation of DNA topoisomerase I in previously untreated non-small cell lung carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-007-9093-0

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-007-9093-0

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

21 January 2018

1 reference

12 December 2020

Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug.

1 reference

12 December 2020

Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro.

1 reference

12 December 2020

Phase I clinical and pharmacological studies of 20-(S)-camptothecin and 20-(S)-9-nitrocamptothecin as anticancer agents

1 reference

12 December 2020

DNA topoisomerase poisons as antitumor drugs

1 reference

12 December 2020

A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.

1 reference

12 December 2020

Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.

1 reference

12 December 2020

Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin

1 reference

12 December 2020

Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing

1 reference

12 December 2020

Point mutations in the topoisomerase I gene in patients with non-small cell lung cancer treated with irinotecan

1 reference

12 December 2020

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells

1 reference

12 December 2020

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

1 reference

12 December 2020

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

1 reference

12 December 2020

Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells

1 reference

12 December 2020

Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.

1 reference

12 December 2020

Camptothecins in clinical development

1 reference

12 December 2020

BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia

1 reference

12 December 2020

Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin

1 reference

12 December 2020

Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin

1 reference

12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

12 December 2020

Mechanisms of resistance to topoisomerase I-targeting drugs

1 reference

12 December 2020

Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

1 reference

12 December 2020

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

1 reference

12 December 2020

Mechanisms of camptothecin resistance by human topoisomerase I mutations

1 reference

12 December 2020

Human multidrug resistance associated protein 4 confers resistance to camptothecins.

1 reference

12 December 2020

10.1007/S10637-007-9093-0

Identifiers

DOI

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Dimensions Publication ID

17 September 2017

1013776290

0 references

Fatcat ID

release_2aqjk4qb25h7zjbvjsdhzyt5fi

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2aqjk4qb25h7zjbvjsdhzyt5fi

24 November 2022

mapped directly with Wikidata item

1 reference