(Q40068077)

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Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation

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scholarly article

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Europe PubMed Central

17 September 2017

Abrogation of p53 by its antisense in MCF-7 breast carcinoma cells increases cyclin D1 via activation of Akt and promotion of cell proliferation (English)

1 reference

Europe PubMed Central

17 September 2017

breast carcinoma

1 reference

based on heuristic

inferred from title

author name string

Rishi Raj Chhipa

1

1 reference

Europe PubMed Central

17 September 2017

Ratna Kumari

2

1 reference

Europe PubMed Central

17 September 2017

Ankur Kumar Upadhyay

3

1 reference

Europe PubMed Central

17 September 2017

Manoj Kumar Bhat

4

1 reference

Europe PubMed Central

17 September 2017

language of work or name

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publication date

4 September 2007

1 reference

Europe PubMed Central

17 September 2017

Experimental Cell Research

1 reference

Europe PubMed Central

17 September 2017

313

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Europe PubMed Central

17 September 2017

19

1 reference

Europe PubMed Central

17 September 2017

3945-3958

1 reference

Europe PubMed Central

17 September 2017

Tumor suppressor p53 mutations and breast cancer: a critical analysis

1 reference

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The p53 tumor suppressor gene in breast cancer

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Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

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p53, the cellular gatekeeper for growth and division

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Establishment and characterization of new murine breast cancer cell lines

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Differential response to radiation of TP53-inactivated cells by overexpression of dominant-negative mutant TP53 or HPVE6.

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Antisense anticancer oligonucleotide therapeutics

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14-3-3sigma mediation of cell cycle progression is p53-independent in response to insulin-like growth factor-I receptor activation

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Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

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Estrogen receptor alpha in human breast cancer: occurrence and significance

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Biosynthesis of alpha fetoprotein by MCF-7 human breast cancer cells

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Mdm2 promotes the rapid degradation of p53

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Regulation of the p53 tumor suppressor protein

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p73, the "assistant" guardian of the genome?

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p53 and breast cancer, an update

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Extension of life-span by introduction of telomerase into normal human cells

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Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin

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Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells

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Differential regulation of signal transduction pathways in wild type and mutated p53 breast cancer epithelial cells by copper and zinc

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Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy.

1 reference

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

1 reference

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Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer

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7 January 2021

Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

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Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.

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Small interfering RNA-mediated down-regulation of caveolin-1 differentially modulates signaling pathways in endothelial cells.

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Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells

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p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis.

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Relevance of breast cancer cell lines as models for breast tumours: an update

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Estradiol stabilizes p53 protein in breast cancer cell line, MCF-7.

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WAF1, a potential mediator of p53 tumor suppression

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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Regulation of the G2/M transition by p53.

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

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p53 loss of function: implications for the processes of immortalization and tumorigenesis

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Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells

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Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1

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High nuclear grade, frequent mitotic activity, cyclin D1 and p53 overexpression are associated with stromal invasion in mammary intracystic papillary carcinoma

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Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.

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p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas

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Regulation of PTEN transcription by p53

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Caveolin-1 in oncogenic transformation, cancer, and metastasis

1 reference

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Caveolin-1 in breast cancer

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Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells

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Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues

1 reference

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Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

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7 January 2021

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10.1016/J.YEXCR.2007.08.022

1 reference

Europe PubMed Central

17 September 2017

1 reference

Europe PubMed Central

17 September 2017

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