(Q40476195)

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Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy.

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scholarly article

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Europe PubMed Central

20 September 2017

Downregulation of wild-type p53 protein by HER-2/neu mediated PI3K pathway activation in human breast cancer cells: its effect on cell proliferation and implication for therapy. (English)

1 reference

Europe PubMed Central

20 September 2017

author name string

Li Zheng

1

1 reference

Europe PubMed Central

20 September 2017

Jia Qiang Ren

2

1 reference

Europe PubMed Central

20 September 2017

Hua Li

3

1 reference

Europe PubMed Central

20 September 2017

Zhao Lu Kong

4

1 reference

Europe PubMed Central

20 September 2017

Hong Guang Zhu

5

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Europe PubMed Central

20 September 2017

publication date

1 December 2004

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Europe PubMed Central

20 September 2017

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Europe PubMed Central

20 September 2017

14

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Europe PubMed Central

20 September 2017

6

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Europe PubMed Central

20 September 2017

497-506

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Europe PubMed Central

20 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.cr.7290253

0 references

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

The p53 tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Regulation of p53 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

MDM2--master regulator of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

p53: death star

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

PI3K/Akt and apoptosis: size matters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

21 January 2018

The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290253

7 January 2021

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10.1038/SJ.CR.7290253

1 reference

Europe PubMed Central

20 September 2017

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1 reference

Europe PubMed Central

20 September 2017

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