(Q40068149)

17 September 2017

Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6. (English)

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17 September 2017

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dengue virus protein NS1

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modulation by virus of host process

inferred from abstract

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author

Antje Blumenthal

3

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17 September 2017

Naphak Modhiran

1

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Katryn J. Stacey

object named as

Katryn J Stacey

6

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Alan G Baxter

object named as

Alan G Baxter

4

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Daniel Watterson

object named as

Daniel Watterson

2

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author name string

Paul R Young

5

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17 September 2017

21 February 2017

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Immunology & Cell Biology

17 September 2017

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17 September 2017

95

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17 September 2017

491-495

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17 September 2017

5

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https://scigraph.springernature.com/pub.10.1038/icb.2017.5

17 September 2017

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cites work

The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Interaction between Ebola virus glycoprotein and host toll-like receptor 4 leads to induction of proinflammatory cytokines and SOCS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Novel bacterial lipoprotein structures conserved in low-GC content gram-positive bacteria are recognized by Toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Structure of the dengue virus glycoprotein non-structural protein 1 by electron microscopy and single-particle analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Determination of the disulfide bond arrangement of dengue virus NS1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Toll-like receptors 1 and 2 cooperatively mediate immune responses to curli, a common amyloid from enterobacterial biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Postulates for validating TLR4 agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Secreted NS1 of Dengue Virus Attaches to the Surface of Cells via Interactions with Heparan Sulfate and Chondroitin Sulfate E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral venous blood in patients with cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Lipopolysaccharide levels are elevated in dengue virus infected patients and correlate with disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Electroporation and DNA-dependent cell death in murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

7 January 2021

Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

7 January 2021

An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

7 January 2021

Optimal conditions for simultaneous purification of mononuclear and polymorphonuclear leucocytes from human blood by the Hypaque-Ficoll method

1 reference

https://api.crossref.org/works/10.1038%2FICB.2017.5

7 January 2021

Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28220810

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/ICB.2017.5

1 reference

PubMed ID

28220810

Dimensions Publication ID

17 September 2017

0 references

1 reference

PubMed ID

28220810