(Q40070342)

17 September 2017

title

Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma (English)

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17 September 2017

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Holger Hetschko

1

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17 September 2017

Valerie Voss

2

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17 September 2017

Sigrid Horn

3

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17 September 2017

Volker Seifert

4

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17 September 2017

Jochen H M Prehn

5

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17 September 2017

Donat Kögel

6

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17 September 2017

publication date

9 October 2007

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Journal of Neuro-Oncology

17 September 2017

published in

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17 September 2017

volume

86

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17 September 2017

issue

3

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17 September 2017

page(s)

265-272

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describes a project that uses

17 September 2017

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https://scigraph.springernature.com/pub.10.1007/s11060-007-9472-6

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cites work

The WHO classification of tumors of the nervous system

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Crossref

https://api.crossref.org/works/10.1007%2FS11060-007-9472-6

Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in established and primary glioma cell lines

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS11060-007-9472-6

Death to the bad guys: targeting cancer via Apo2L/TRAIL.

21 January 2018

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12 December 2020

Apoptosis in gliomas, and its role in their current and future treatment

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12 December 2020

Recent developments in the use of chemotherapy in brain tumours.

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12 December 2020

Killing cancer cells by flipping the Bcl-2/Bax switch.

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12 December 2020

TRAIL/Apo-2L: mechanisms and clinical applications in cancer

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12 December 2020

Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation

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12 December 2020

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

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12 December 2020

Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death.

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12 December 2020

Mitochondrial membrane permeabilization in cell death

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12 December 2020

Malignant glioma: genetics and biology of a grave matter.

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12 December 2020

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

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12 December 2020

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

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12 December 2020

Regulation of gene expression by the amyloid precursor protein: inhibition of the JNK/c-Jun pathway.

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12 December 2020

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

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12 December 2020

BH3-domain mimetic compound BH3I-2' induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria.

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12 December 2020

Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells.

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12 December 2020

Expression of bcl-2, bax and bcl-xl in human gliomas: a re-appraisal.

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12 December 2020

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

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12 December 2020

A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo

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12 December 2020

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

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12 December 2020

APO2 ligand: a novel lethal weapon against malignant glioma?

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12 December 2020

Genomic alterations in human malignant glioma cells associate with the cell resistance to the combination treatment with tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy

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12 December 2020

TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways.

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12 December 2020

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

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12 December 2020

10.1007/S11060-007-9472-6

Identifiers

DOI

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Dimensions Publication ID

17 September 2017

1052306399

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