(Q42471712)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Regulation of gene expression by the amyloid precursor protein: inhibition of the JNK/c-Jun pathway (English)

1 reference

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6 January 2020

4

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6 January 2020

author name string

Kögel D

series ordinal

1

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6 January 2020

Schomburg R

series ordinal

2

1 reference

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6 January 2020

Copanaki E

series ordinal

3

1 reference

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6 January 2020

language of work or name

1 reference

1 January 2005

1 reference

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Cell Death & Differentiation

6 January 2020

published in

1 reference

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6 January 2020

volume

12

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6 January 2020

issue

1

1 reference

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6 January 2020

page(s)

1-9

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401495

6 January 2020

exact match

0 references

cites work

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Deciphering the genetic basis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

New frontiers in Alzheimer's disease genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

The JIP group of mitogen-activated protein kinase scaffold proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Selective expression of JNK isoforms and stress-specific JNK activity in different neural cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

ASK1-signaling promotes c-Myc protein stability during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Mixed lineage kinase activity of indolocarbazole analogues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Fatal shift of signal transduction is an integral part of neuronal differentiation: JNKs realize TNFalpha-mediated apoptosis in neuronlike, but not naive, PC12 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

TPO1, a member of a novel protein family, is developmentally regulated in cultured oligodendrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Cytosolic Ca(2+) signal is involved in regulating UV-induced apoptosis in hela cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Apoptosis in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Matricellular proteins: extracellular modulators of cell function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Upregulation and antiapoptotic role of endogenous Alzheimer amyloid precursor protein in dorsal root ganglion neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Targeting JNK for therapeutic benefit: from junk to gold?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Targeting the JNK pathway for therapeutic benefit in CNS disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

JNK activation is associated with intracellular beta-amyloid accumulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Anti-apoptotic wild-type Alzheimer amyloid precursor protein signaling involves the p38 mitogen-activated protein kinase/MEF2 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Purification and catalytic properties of human caspase family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401495

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401495

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

1004705176

0 references

1 reference