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Regulation of gene expression by the amyloid precursor protein: inhibition of the JNK/c-Jun pathway.
scientific article published on January 2005
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
title
Regulation of gene expression by the amyloid precursor protein: inhibition of the JNK/c-Jun pathway
(English)
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
author
Jochen Prehn
series ordinal
4
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
author name string
Kögel D
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
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6 January 2020
Schomburg R
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2
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
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6 January 2020
Copanaki E
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3
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
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6 January 2020
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English
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publication date
1 January 2005
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Europe PubMed Central
PubMed publication ID
15592359
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retrieved
6 January 2020
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
volume
12
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Europe PubMed Central
PubMed publication ID
15592359
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6 January 2020
issue
1
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PubMed publication ID
15592359
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
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6 January 2020
page(s)
1-9
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Europe PubMed Central
PubMed publication ID
15592359
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retrieved
6 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401495
0 references
cites work
Alzheimer's disease: genes, proteins, and therapy
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Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
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Deciphering the genetic basis of Alzheimer's disease
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Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.
1 reference
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New frontiers in Alzheimer's disease genetics
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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex
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Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.
1 reference
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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
1 reference
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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner
1 reference
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Crossref
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retrieved
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c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK
1 reference
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Crossref
reference URL
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7 January 2021
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Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).
1 reference
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Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism
1 reference
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Crossref
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Requirement of the JIP1 scaffold protein for stress-induced JNK activation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
The JIP group of mitogen-activated protein kinase scaffold proteins
1 reference
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Crossref
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The c-Jun transcription factor--bipotential mediator of neuronal death, survival and regeneration
1 reference
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The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis
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Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation
1 reference
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Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway
1 reference
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Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells
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c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells
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Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease
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Selective expression of JNK isoforms and stress-specific JNK activity in different neural cell lines
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ASK1-signaling promotes c-Myc protein stability during apoptosis
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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
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Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.
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Fatal shift of signal transduction is an integral part of neuronal differentiation: JNKs realize TNFalpha-mediated apoptosis in neuronlike, but not naive, PC12 cells.
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Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes
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Upregulation and antiapoptotic role of endogenous Alzheimer amyloid precursor protein in dorsal root ganglion neurons.
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1 reference
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1 reference
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1 reference
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Crossref
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1 reference
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Basic local alignment search tool
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401495
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
Dimensions Publication ID
1004705176
0 references
PubMed publication ID
15592359
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15592359
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
ResearchGate publication ID
8136415
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