(Q40081763)

17 September 2017

title

Inhibitors of histone deacetylases induce tumor-selective cytotoxicity through modulating Aurora-A kinase (English)

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17 September 2017

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8

Yung-Jue Bang

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17 September 2017

9

Tae-You Kim

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17 September 2017

2

Hyun-Soon Jong

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17 September 2017

4

Yeonjoo Jung

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17 September 2017

5

Keun-Wook Lee

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17 September 2017

Jung-Hyun Park

1

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17 September 2017

Sang Gyun Kim

series ordinal

3

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17 September 2017

Ju-Hee Lee

series ordinal

6

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17 September 2017

Dae-Kee Kim

series ordinal

7

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17 September 2017

publication date

13 September 2007

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Journal of Molecular Medicine

17 September 2017

published in

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17 September 2017

volume

86

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17 September 2017

issue

1

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17 September 2017

page(s)

117-128

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https://scigraph.springernature.com/pub.10.1007/s00109-007-0260-8

17 September 2017

exact match

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cites work

Inhibitors of histone deacetylases alter kinetochore assembly by disrupting pericentromeric heterochromatin.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-007-0260-8

Surgeons as an Integral Part of the Cancer Research Team

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-007-0260-8

The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases

21 January 2018

1 reference

12 December 2020

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

1 reference

12 December 2020

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

1 reference

12 December 2020

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

1 reference

12 December 2020

Acetylation of proteins as novel target for antitumor therapy: review article.

1 reference

12 December 2020

HP1 and the dynamics of heterochromatin maintenance

1 reference

12 December 2020

Amide Analogues of Trichostatin A as Inhibitors of Histone Deacetylase and Inducers of Terminal Cell Differentiation

1 reference

12 December 2020

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

1 reference

12 December 2020

Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents

1 reference

12 December 2020

Targeting Aurora-2 kinase in cancer.

1 reference

12 December 2020

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

1 reference

12 December 2020

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

1 reference

12 December 2020

Chemical ablation of androgen receptor in prostate cancer cells by the histone deacetylase inhibitor LAQ824.

1 reference

12 December 2020

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

1 reference

12 December 2020

A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

1 reference

12 December 2020

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

1 reference

12 December 2020

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

12 December 2020

N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).

1 reference

12 December 2020

Induction of polyploidy by histone deacetylase inhibitor: a pathway for antitumor effects

1 reference

12 December 2020

Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation

1 reference

12 December 2020

Histone deacetylases and cancer: causes and therapies

1 reference

12 December 2020

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

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12 December 2020

Aurora-kinase inhibitors as anticancer agents

1 reference

12 December 2020

Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation

1 reference

12 December 2020

Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B

1 reference

12 December 2020

Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects

1 reference

12 December 2020

Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.

1 reference

12 December 2020

Function and regulation of Aurora/Ipl1p kinase family in cell division

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12 December 2020

Tumor cell-selective cytotoxicity by targeting cell cycle checkpoints.

1 reference

12 December 2020

Global role for chromatin remodeling enzymes in mitotic gene expression

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12 December 2020

Polar expeditions--provisioning the centrosome for mitosis.

1 reference

12 December 2020

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

1 reference

12 December 2020

Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases

1 reference

12 December 2020

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin

1 reference

12 December 2020

10.1007/S00109-007-0260-8

Identifiers

DOI

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17 September 2017

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