(Q40082182)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

4

Sabine Gilch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

5

Peter Riederer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1

Seong-Wook Yun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Alexa Ertmer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Eckhard Flechsig

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Manfred Gerlach

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Michael A Klein

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

published in

Journal of NeuroVirology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

328-337

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17849316%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1080/13550280701361516

7 January 2020

exact match

0 references

cites work

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

1 reference

12 December 2020

Mice devoid of PrP are resistant to scrapie

1 reference

12 December 2020

Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

1 reference

12 December 2020

Prion diseases--close to effective therapy?

1 reference

12 December 2020

The kinase inhibitor STI571 reverses the Bcr-Abl induced point mutation frequencies observed in pre-leukemic P190(Bcr-Abl) transgenic mice

1 reference

12 December 2020

Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions

1 reference

12 December 2020

Oxidative stress in the brain at early preclinical stages of mouse scrapie.

1 reference

12 December 2020

PrPC directly interacts with proteins involved in signaling pathways

1 reference

12 December 2020

The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells.

1 reference

12 December 2020

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins

1 reference

12 December 2020

Branched polyamines cure prion-infected neuroblastoma cells

1 reference

12 December 2020

Neuropathology of prion diseases

1 reference

12 December 2020

Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cells

1 reference

12 December 2020

Gleevec inhibits β-amyloid production but not Notch cleavage

1 reference

12 December 2020

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

1 reference

12 December 2020

1 reference

12 December 2020

Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion

1 reference

12 December 2020

Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

1 reference

12 December 2020

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1 reference

12 December 2020

Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux

1 reference

12 December 2020

Isolated central nervous system relapse in lymphoid blast crisis chronic myeloid leukemia and acute lymphoblastic leukemia in patients on imatinib therapy

1 reference

12 December 2020

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

1 reference

12 December 2020

Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4+ T-cell tolerance

1 reference

12 December 2020

Neuroprotective functions of prion protein

1 reference

12 December 2020

Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models

1 reference

12 December 2020

Mammalian prion protein suppresses Bax-induced cell death in yeast

1 reference

12 December 2020

Approaches to therapy of prion diseases

1 reference

12 December 2020

Active transport of imatinib into and out of cells: implications for drug resistance

1 reference

12 December 2020

Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice.

1 reference

12 December 2020

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

1 reference

12 December 2020

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

1 reference

12 December 2020

Central nervous system failure in patients with chronic myelogenous leukemia lymphoid blast crisis and Philadelphia chromosome positive acute lymphoblastic leukemia treated with imatinib (STI-571).

1 reference

12 December 2020

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

1 reference

12 December 2020

Prions, cytokines, and chemokines: a meeting in lymphoid organs

1 reference

12 December 2020

Prion clearance in bigenic mice

1 reference

12 December 2020

PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain.

1 reference

12 December 2020

Altered behavioural response to acute stress in mice lacking cellular prion protein

1 reference

12 December 2020

In vivo efficacy of STI571 in xenografted human small cell lung cancer alone or combined with chemotherapy

1 reference

12 December 2020

Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons

1 reference

12 December 2020

hOCT 1 and resistance to imatinib

1 reference

12 December 2020

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1 reference

12 December 2020

Complement facilitates early prion pathogenesis.

1 reference

12 December 2020

Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.

1 reference

12 December 2020

The CNS is a sanctuary for leukemic cells in mice receiving imatinib mesylate for Bcr/Abl-induced leukemia

1 reference

12 December 2020

Incubation periods in six models of intraperitoneally injected scrapie depend mainly on the dynamics of agent replication within the nervous system and not the lymphoreticular system

1 reference

12 December 2020

Cloning and functional expression of a mouse liver organic cation transporter

1 reference

12 December 2020

Elimination of prions by branched polyamines and implications for therapeutics

1 reference

12 December 2020

Signal transduction through prion protein

1 reference

12 December 2020

Lysosomal cysteine proteases regulate antigen presentation

1 reference

12 December 2020

Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid

1 reference

12 December 2020

MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

1 reference

12 December 2020