(Q40093030)

17 September 2017

The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections (English)

1 reference

17 September 2017

0 references

15

Gerold Schmitt-Ulms

1 reference

17 September 2017

Joel C Watts

1

1 reference

17 September 2017

Bettina Drisaldi

2

1 reference

17 September 2017

Vivian Ng

3

1 reference

17 September 2017

Jing Yang

4

1 reference

17 September 2017

Bob Strome

5

1 reference

17 September 2017

Patrick Horne

6

1 reference

17 September 2017

Man-Sun Sy

7

1 reference

17 September 2017

Larry Yoong

8

1 reference

17 September 2017

Rebecca Young

9

1 reference

17 September 2017

Peter Mastrangelo

10

1 reference

17 September 2017

Catherine Bergeron

11

1 reference

17 September 2017

Paul E Fraser

12

1 reference

17 September 2017

George A Carlson

13

1 reference

17 September 2017

Howard T J Mount

14

1 reference

17 September 2017

David Westaway

16

1 reference

17 September 2017

language of work or name

English

0 references

publication date

16 August 2007

1 reference

17 September 2017

1 reference

17 September 2017

26

1 reference

17 September 2017

17

1 reference

17 September 2017

4038-4050

1 reference

Lethal recessive myelin toxicity of prion protein lacking its central domain

17 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Fusion of Doppel to octapeptide repeat and N-terminal half of hydrophobic region of prion protein confers resistance to serum deprivation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Prion protein accumulation and neuroprotection in hypoxic brain damage

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

PrPSc binding antibodies are potent inhibitors of prion replication in cell lines.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Dual mechanisms for shedding of the cellular prion protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Genomic characterization of the human prion protein (PrP) gene locus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Absence of the prion protein homologue Doppel causes male sterility

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Cellular prion protein transduces neuroprotective signals

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Doppel-induced cerebellar degeneration in transgenic mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Two different neurodegenerative diseases caused by proteins with similar structures

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Early loss of dendritic spines in murine scrapie revealed by confocal analysis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Overexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

NMR structure of the mouse prion protein domain PrP(121-231)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Mice devoid of PrP are resistant to scrapie

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Scrapie prion proteins are synthesized in neurons

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Purification and properties of the cellular prion protein from Syrian hamster brain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Regional mapping of prion proteins in brain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Prion protein protects human neurons against Bax-mediated apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Upregulation of cellular prion protein (PrPc) after focal cerebral ischemia and influence of lesion severity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Scrapie-specific neuronal lesions are independent of neuronal PrP expression

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Prions prevent neuronal cell-line death.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Scrapie infection alters the membrane and synaptic properties of mouse hippocampal CA1 pyramidal neurones.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Normal host prion protein necessary for scrapie-induced neurotoxicity.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Truncated forms of the human prion protein in normal brain and in prion diseases.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950727

Analysis of doppel protein toxicity

2 December 2018

1 reference

12 December 2020

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

1 reference

12 December 2020

Linkage of prion protein and scrapie incubation time genes

1 reference

12 December 2020

Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis

1 reference

12 December 2020

Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus

1 reference

12 December 2020

Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601830

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7601830

1 reference

17 September 2017

1 reference

17 September 2017

PubMed publication ID

17703189

1 reference