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Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context.
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1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
title
Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
author
Maria A Theodoraki
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
author name string
Mary Kunjappu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
David W Sternberg
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Avrom J Caplan
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
language of work or name
English
0 references
publication date
6 July 2007
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
published in
Experimental Cell Research
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
volume
313
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
page(s)
3851-3858
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
issue
18
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
cites work
Molecular chaperones and protein kinase quality control.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Ba/F3 cells and their use in kinase drug discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Up-regulation of heat shock protein 27 induces resistance to 17-allylamino-demethoxygeldanamycin through a glutathione-mediated mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
HSP90: a rising star on the horizon of anticancer targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
HSP90 and the chaperoning of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Phosphatidylinositol 3-kinase p85{alpha} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
ErbB2 degradation mediated by the co-chaperone protein CHIP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Identification of ErbB-2 kinase domain motifs required for geldanamycin-induced degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Folding of newly translated proteins in vivo: the role of molecular chaperones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
The oncoprotein kinase chaperone CDC37 functions as an oncogene in mice and collaborates with both c-myc and cyclin D1 in transformation of multiple tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
22 September 2017
ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
25 September 2017
Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
25 September 2017
CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
15 June 2018
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
15 June 2018
Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
15 June 2018
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
20 August 2018
Hsp90 Recognizes a Common Surface on Client Kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2099248
retrieved
2 December 2018
Identifiers
DOI
10.1016/J.YEXCR.2007.06.022
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PMCID
2099248
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PubMed ID
17643429
1 reference
stated in
Europe PubMed Central
PMCID
2099248
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17643429%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
ResearchGate publication ID
6196004
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