(Q40107440)

17 September 2017

1 reference

title

Short-term tests with biochemical end points relevant to the prediction of carcinogenic potential of drugs (English)

1 reference

17 September 2017

Short-Term Tests with Biochemical End Points Relevant to the Prediction of Carcinogenic Potential of Drugs (English)

1 reference

https://api.crossref.org/works/10.3109/03602538308991398

25 August 2023

author name string

Martin RA

1

1 reference

17 September 2017

de la Iglesia FA

2

1 reference

17 September 2017

language of work or name

English

0 references

publication date

1 January 1983

1 reference

full work available at URL

17 September 2017

http://www.tandfonline.com/doi/pdf/10.3109/03602538308991398

1 reference

https://api.crossref.org/works/10.3109/03602538308991398

25 August 2023

published in

Drug Metabolism Reviews

1 reference

17 September 2017

volume

14

1 reference

17 September 2017

issue

3

1 reference

17 September 2017

page(s)

513-555

1 reference

Short-term tests for mutagenesis and carcinogenesis in drug toxicology: how to test and when to test is the question

17 September 2017

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Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use.

21 January 2018

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In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons

21 January 2018

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Short term screening tests for carcinogens

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Effect of human gastric juice on the mutagenicity of chemicals.

21 January 2018

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Some factors determining the concentration of liver proteins for optimal mutagenicity of chemicals in the salmonella/microsome assay

21 January 2018

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Initiation of chemical carcinogenesis requires cell proliferation

21 January 2018

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On the interaction of carcinogens with DNA.

21 January 2018

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21 January 2018

Chemical carcinogenesis

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EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.

21 January 2018

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Nuclear proteins and chemical carcinogenesis

21 January 2018

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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602538308991398

Binding of metabolites of dietary 4-dimethyl-aminoazobenzene and 2-methyl-4-dimethylamino-azobenzene to rat liver DNA and protein of subcellular fractions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Species difference in the binding of aflatoxin B1 to hepatic macromolecules

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602538308991398

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602538308991398

Carcinogenicity of 8-nitroquinoline in Sprague-Dawley rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

In vivo binding of 2,3,6,2′,3′,6′-hexachlorobiphenyl and 2,4,5,2′,4′,5′-hexachlorobiphenyl to mouse liver macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Regulation of the binding of 7,12-dimethylbenz[a]anthracene to DNA of cultured murine epidermal cells at metabolic level: Competition of the binding by polycyclic aromatic hydrocarbons and by other precarcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Dna Binding and Mutagenicity of 7-Substituted Derivatives of Benz[A]Anthracelje

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Comparative studies on the covalent binding of the carcinogen benzo(a)pyrene to DNA in various model systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Binding of the carcinogen 2-acetamidophenanthrene to rat liver nucleic acids: Lack of correlation with carcinogenic activity, and failure of the hydroxamic acid ester model for in vivo activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Mechanism of the carcinogenic action of benzene: irreversible binding to rat liver DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

DNA repair synthesis of cultured human cells as a rapid bioassay for chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

DNA Repair Synthesis in Mammalian Cells exposed to a Series of Oncogenic and Non-Oncogenic Derivatives of 4-Nitroquinoline 1-Oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

In vivo repair of rat liver DNA damaged by dimethylnitrosamine or diethylnitrosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Rapid test to detect agents that damage human DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

DNA repair inhibition: A possible mechanism of action of co-carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Utilization of 3H from deoxyuridine and thymidine for synthesis of DNA and other macromolecules in various organs of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

The relationship of thymidine metabolism to the use of fractional incorporation as a measure of DNA synthesis and tissue proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Use of 3 H-thymidine for measurement of DNA synthesis in rat liver--a warning

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

New Giemsa method for the differential staining of sister chromatids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Fractionation of DNA from mammalian cells by alkaline elution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Regulation of amino acid decarboxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

1,4-Diaminobutane (putrescine), spermidine, and spermine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Inhibition of ornithine decarboxylase of HeLa cells by diamines and polyamines. Effect on cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Drug stimulation of putrescine and spermidine syntheses. Relationships to enhancement of ribonucleic acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Synthesis and accumulation of polyamines in rat liver regenerating after treatment with carbon tetrachloride

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

SPERMIDINE AND SPERMINE IN RAT TISSUES AT DIFFERENT AGES.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Polyamine accumulation during lymphocyte transformation and its relation to the synthesis, processing, and accumulation of ribonucleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

The effect of a single intraperitoneal dose of the hepatocarcinogen 4-dimethylaminoazobenzene on the rough-surfaced endoplasmic reticulum of the liver of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

The effects of ribosomes on the activity of a membrane bound enzyme catalysing thiol-disulphide interchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Microsomal aspects of carcinogenesis and neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Ribosome-membrane interaction. Nondestructive disassembly of rat liver rough microsomes into ribosomal and membranous components

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Membrane-bound ribosomes of myeloma cells. III. The role of the messenger RNA and the nascent polypeptide chain in the binding of ribosomes to membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

A sub-population of rat liver membrane-bound ribosomes that are detached in vitro by carcinogens and centrifugation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

A LIGHT AND ELECTRON MICROSCOPE STUDY OF THE MORPHOLOGICAL CHANGES INDUCED IN RAT LIVER CELLS BY THE AZO DYE 2-ME-DAB

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Microsomal membrane alterations during acute ethionine toxicity and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

An evaluation of 6 short-term tests for detecting organic chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Biochemical Monitoring of Cancer: A Review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Evolution of alpha-fetoprotein serum levels throughout life in humans and rats, and during pregnancy in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Occurrence of alpha‐fetoprotein in acute viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

alpha-fetoprotein in noneoplastic hepatic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Serum Alpha-Fetoprotein: A Prognostic Indicator of Liver-cell Necrosis and Regeneration Following Experimental Injury by Galactosamine in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Clinical aspects of α1‐fetoprotein determination in human liver cancer and in humans and experimental animals at carcinogenic risk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Carcinoembryonic antigen.Report of a screening study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Carcinoembryonic antigen present in human colonic neoplasms serially propagated in hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Antitrypsin phenotypes in St. Louis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Hepatocellular Carcinoma and Intermediateα1-Antitrypsin Deficiency (MZ Phenotype)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Immunocytochemical localization of oncodevelopmental proteins in human germ cell and hepatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

The concentration of alpha-1-antitrypsin in cerebrospinal fluid and serum in a series of 40 intracranial tumors

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602538308991398

21 January 2018

Ovarian tumor antigens

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https://api.crossref.org/works/10.3109%2F03602538308991398

Studies on an oncofetal antigen, POA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

‘Solubilization’ of Carcinogens with Nucleic Acid Solutions. The Interaction of p-Dimethylaminoazobenzene with Ribonucleic Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Double-stranded DNA stereoselectively binds benzo(a)pyrene diol epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602538308991398

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

21 January 2018

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Disruption by Carcinogens of the Hormone Dependent Association of Membranes with Polysomes

21 January 2018

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Low Carcinogenicity of the K-Region Epoxides of 7-Methylbenz(a)-anthracene and Benz (a) anthracene in the Mouse and Rat

21 January 2018

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DNA binding of benzo[a]pyrene metabolites. Effects of substrate and microsomal protein concentration in vitro, dietary contaminants, and tissue differences

25 August 2023

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Effect of decreased glucuronidation and sulfation on covalent binding of naphthalene in isolated rat hepatocytes

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The effects of cytochrome P-450-448 inhibitors on the binding of benzo(a)pyrene and derivatives to DNA upon microsomal activation

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Covalent binding of ethinylestradiol and estrone to rat liver DNA in vivo.

25 August 2023

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Saccharin does not bind to DNA of liver or bladder in the rat

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In vivo covalent binding of aflatoxin B1 and aflatoxin M1 to liver DNA of rat, mouse and pig

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Covalent binding of drug metabolites to DNA ? a tool of predictive value?

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Defect in DNA Synthesis in Skin of Patients with Xeroderma Pigmentosum Demonstrated in vivo

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Effects of vinylidene chloride on DNA synthesis and DNA repair in the rat and mouse: a comparative study with dimethylnitrosamine

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Detection by alkaline elution of rat liver DNA damage induced by simultaneous subacute administration of nitrite and aminopyrine

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Regulation of ornithine decarboxylase activity by putrescine and spermidine in rat liver

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25 August 2023

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Effects of dietary butylated hydroxytoluene and phenobarbital on the activities of ornithine decarboxylase and thymidine kinase in rat liver and lung

25 August 2023

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Stimulation of polyamine synthesis in relation to nucleic acids in regenerating rat liver

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Polyamine synthesis during initial phases of stress-induced cardiac hypertrophy

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Polyamine biogenesis in left ventricle of the rat heart after aortic constriction

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Putrescine and related amines as growth factors for a mammalian cell line

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Identification of a Growth Factor produced by Human Fibroblasts in vitro as Putrescine

25 August 2023

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Plasma spermine concentrations of patients with benign and malignant tumours of the breast or prostate

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Cell loss as a factor in the growth rate of human tumours

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The effects of aflatoxin B(1) and steroid hormones on polysome binding to microsomal membranes as measured by the activity of an enzyme catalysing disulphide interchange

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17 September 2017

1 reference