(Q40116480)

17 September 2017

Tyrosine kinase inhibitor, methyl 2,5-dihydromethylcinnimate, induces PML nuclear body formation and apoptosis in tumor cells (English)

1 reference

17 September 2017

Naoyuki Komura

1

1 reference

17 September 2017

Mayako Asakawa

series ordinal

2

1 reference

17 September 2017

Kazuo Umezawa

series ordinal

3

1 reference

17 September 2017

Kaoru Segawa

series ordinal

4

1 reference

17 September 2017

language of work or name

English

0 references

publication date

1 April 2007

1 reference

Experimental Cell Research

17 September 2017

1 reference

17 September 2017

313

1 reference

17 September 2017

13

1 reference

17 September 2017

2753-2765

1 reference

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

17 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

How acute promyelocytic leukaemia revived arsenic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

The transcriptional role of PML and the nuclear body

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

DNA viruses and viral proteins that interact with PML nuclear bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Role and fate of PML nuclear bodies in response to interferon and viral infections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

The role of PML in tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Regulation and localization of the Bloom syndrome protein in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PML colocalizes with and stabilizes the DNA damage response protein TopBP1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Atmospheric carbon dioxide concentrations over the past 60 million years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PUMA induces the rapid apoptosis of colorectal cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PUMA, a novel proapoptotic gene, is induced by p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Altered retinoic acid receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Opposing effects of PML and PML/RAR alpha on STAT3 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Role of promyelocytic leukemia (PML) protein in tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

The molecular genetics of acute promyelocytic leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Covalent modification of PML by the sentrin family of ubiquitin-like proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Protein modification by SUMO

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Induction of morphological change by tyrosine kinase inhibitors in Rous sarcoma virus-transformed rat kidney cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Differential SMN2 expression associated with SMA severity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

Regulation of p53 function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

The complexity of p53 modulation: emerging patterns from divergent signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.032

10.1016/J.YEXCR.2007.03.032

7 January 2021

Identifiers

DOI

1 reference

17 September 2017

1 reference