(Q40116847)

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Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

0 references

author name string

Oetjen E

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Blume R

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Cierny I

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Schlag C

4

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Kutschenko A

5

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Krätzner R

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Stein R

7

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Knepel W

8

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

publication date

22 June 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

1678-1687

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0712-2

21 January 2018

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0712-2

21 January 2018

MAFA controls genes implicated in insulin biosynthesis and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose induces MafA expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Luciferase reporter gene vectors for analysis of promoters and enhancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural history of beta-cell function in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of p300-mediated transcription by the kinase MEKK1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct properties of the cAMP-responsive element of the rat insulin I gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Hormone-Producing Clonal Lines of Human Choriocarcinoma1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How obesity causes diabetes: not a tall tale

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta cell death in hyperglycaemic Psammomys obesus is not cytokine-mediated

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cyclic AMP response element-binding protein/cyclic AMP response element-mediated transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MafA is a key regulator of glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of PDX-1 in activation of human insulin gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TAO of MEKK

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factors recognizing overlapping C1-A2 binding sites positively regulate insulin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of insulin gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 diabetes-a matter of beta-cell life and death?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of MafA is essential for its transcriptional and biological properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene-specific transcriptional activity of the insulin cAMP-responsive element is conferred by NF-Y in combination with cAMP response element-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 diabetes: principles of pathogenesis and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17583797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-007-0712-2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

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