(Q40118820)

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Basic concepts in population modeling, simulation, and model-based drug development-part 2: introduction to pharmacokinetic modeling methods.

scientific article published on 17 April 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Basic concepts in population modeling, simulation, and model-based drug development-part 2: introduction to pharmacokinetic modeling methods (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

pharmacokinetics

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based on heuristic

inferred from title

Richard N Upton

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

D R Mould

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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17 April 2013

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

CPT: pharmacometrics & systems pharmacology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

e38

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Fundamentals of population pharmacokinetic modelling: modelling and software.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Impact of low percentage of data below the quantification limit on parameter estimates of pharmacokinetic models

1 reference

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22 September 2017

Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models

1 reference

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22 September 2017

Handling data below the limit of quantification in mixed effect models

1 reference

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22 September 2017

The use of clinical irrelevance criteria in covariate model building with application to dofetilide pharmacokinetic data

1 reference

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22 September 2017

Likelihood based approaches to handling data below the quantification limit using NONMEM VI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Population pharmacokinetic model for docetaxel in patients with varying degrees of liver function: incorporating cytochrome P4503A activity measurements

1 reference

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22 September 2017

Diagnosing model diagnostics

1 reference

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22 September 2017

Whole-body physiologically based pharmacokinetic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Comparison of stepwise covariate model building strategies in population pharmacokinetic-pharmacodynamic analysis

1 reference

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22 September 2017

Red blood cells: a neglected compartment in topotecan pharmacokinetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Ways to fit a PK model with some data below the quantification limit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Pharmacokinetics of oral acyclovir in neonates and in infants: a population analysis

1 reference

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22 September 2017

Estimating data transformations in nonlinear mixed effects models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

22 September 2017

Clearance approaches in pharmacology.

1 reference

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22 September 2017

Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs

1 reference

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22 September 2017

Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions

1 reference

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17 June 2018

A size standard for pharmacokinetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

17 June 2018

The importance of modeling interoccasion variability in population pharmacokinetic analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

17 June 2018

A physiologically-based recirculatory meta-model for nasal fentanyl in man.

1 reference

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20 August 2018

Comparison of Nonmem 7.2 estimation methods and parallel processing efficiency on a target-mediated drug disposition model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Population Pharmacokinetic‐Pharmacodynamic Modeling of Biological Agents: When Modeling Meets Reality

1 reference

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20 August 2018

Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Derivation of various NONMEM estimation methods.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Population pharmacokinetic and adverse event analysis of topotecan in patients with solid tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Evaluating pharmacokinetic/pharmacodynamic models using the posterior predictive check

1 reference

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20 August 2018

Hydraulic analog for simultaneous representation of pharmacokinetics and pharmacodynamics: application to vecuronium.

1 reference

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20 August 2018

Three new residual error models for population PK/PD analyses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Interaction between structural, statistical, and covariate models in population pharmacokinetic analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Variance components testing in the longitudinal mixed effects model

1 reference

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20 August 2018

Bayesian individualization of pharmacokinetics: simple implementation and comparison with non-Bayesian methods.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636497

20 August 2018

Fundamentals of Population Pharmacokinetic Modelling : Modelling and Software

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

21 January 2018

Log-normal Distributions across the Sciences: Keys and Clues

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

21 January 2018

Out of India, thrice: diversification of Asian forest scorpions reveals three colonizations of Southeast Asia

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Common noncompartmental pharmacokinetic variables: are they normally or log-normally distributed?

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Assessment of type I error rates for the statistical sub-model in NONMEM

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Semiparametric distributions with estimated shape parameters

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Power, selection bias and predictive performance of the Population Pharmacokinetic Covariate Model

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Bootstrap approach for constructing confidence intervals for population pharmacokinetic parameters. I: A use of bootstrap standard error

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2013.14

31 March 2020

Pharmacokinetics tricks and traps: flip-flop models

1 reference

https://pubmed.ncbi.nlm.nih.gov/23887688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/PSP.2013.14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23887688%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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