(Q40122801)

English

The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells.

scientific article published on 7 June 2007

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

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author name string

J Burthem

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

K Rees-Unwin

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

R Mottram

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

J Adams

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

G S Lucas

5

1 reference

Europe PubMed Central

PubMed publication ID

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31 December 2019

publication date

7 June 2007

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

21

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1708-1714

1 reference

Europe PubMed Central

PubMed publication ID

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31 December 2019

Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center: a 4.5-year follow-up

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

GDIs: central regulatory molecules in Rho GTPase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Two distinct cytoplasmic regions of the beta2 integrin chain regulate RhoA function during phagocytosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

BCR/ABL induces multiple abnormalities of cytoskeletal function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of abnormal integrin-cytoskeletal interactions in impaired beta1 integrin function in chronic myelogenous leukemia hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic myelogenous leukemia primitive hematopoietic progenitors demonstrate increased sensitivity to growth factor-induced proliferation and maturation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Biology of chronic myelogenous leukemia--signaling pathways of initiation and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

No correlation between the proliferative status of Bcr-Abl positive cell lines and the proapoptotic activity of imatinib mesylate (Gleevec/Glivec).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic myelogenous leukaemia CD34+ cells exit G0/G1 phases of cell cycle more rapidly than normal marrow CD34+ cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Reply: The long-term response to imatinib treatment of CML

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404762

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2404762

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554385%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

ResearchGate publication ID

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