(Q40125098)

17 September 2017

Predicted disorder-to-order transition mutations in IκBα disrupt function (English)

1 reference

17 September 2017

Lilia M Iakoucheva

6

0 references

author name string

Holly Dembinski

1

1 reference

17 September 2017

Kevin Wismer

2

1 reference

17 September 2017

Deepa Balasubramaniam

3

1 reference

17 September 2017

Hector A Gonzalez

4

1 reference

17 September 2017

Vera Alverdi

5

1 reference

17 September 2017

Elizabeth A Komives

7

1 reference

17 September 2017

language of work or name

English

0 references

publication date

6 March 2014

1 reference

Physical Chemistry Chemical Physics

17 September 2017

1 reference

17 September 2017

16

1 reference

17 September 2017

14

1 reference

17 September 2017

6480-6485

1 reference

Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA

17 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Disease-associated mutations disrupt functionally important regions of intrinsic protein disorder

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Disease mutations in disordered regions--exception to the rule?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Flexible Regions within IκBα Create the Ubiquitin-independent Degradation Signal

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Comparing models of evolution for ordered and disordered proteins.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Linking folding and binding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

High-speed and high-resolution UPLC separation at zero degrees Celsius

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Pre-folding IkappaBalpha alters control of NF-kappaB signaling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Binding-induced folding of a natively unstructured transcription factor.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

NF-kappaB dictates the degradation pathway of IkappaBalpha

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Binding of mRNA to the bacterial translation initiation complex

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

The energy landscape of modular repeat proteins: topology determines folding mechanism in the ankyrin family

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040282

Predicting Protein Disorder for N-, C-, and Internal Regions

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24605363

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1039/C3CP54427C

1 reference

17 September 2017

1 reference

17 September 2017

PubMed publication ID

24605363

1 reference