(Q40138198)

17 September 2017

title

C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation (English)

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17 September 2017

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5

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17 September 2017

Vegesna Radha

1

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17 September 2017

Ajumeera Rajanna

series ordinal

2

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17 September 2017

Aninda Mitra

series ordinal

3

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17 September 2017

Nandini Rangaraj

series ordinal

4

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17 September 2017

language of work or name

English

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publication date

30 March 2007

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Experimental Cell Research

17 September 2017

published in

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17 September 2017

volume

313

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17 September 2017

issue

11

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17 September 2017

page(s)

2476-2492

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C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

17 September 2017

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1 reference

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7 January 2021

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Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

7 January 2021

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Src-CrkII-C3G-dependent Activation of Rap1 Switches Growth Hormone-stimulated p44/42 MAP Kinase and JNK/SAPK Activities

7 January 2021

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The association of CRKII with C3G can be regulated by integrins and defines a novel means to regulate the mitogen-activated protein kinases

7 January 2021

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Physical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domain

7 January 2021

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Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1.

7 January 2021

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Crk activation of JNK via C3G and R-Ras

7 January 2021

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PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

7 January 2021

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C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of anchorage-independent growth.

7 January 2021

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C3G regulates the size of the cerebral cortex neural precursor population

7 January 2021

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Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G

7 January 2021

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Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

7 January 2021

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Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

7 January 2021

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Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton

7 January 2021

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Transformation suppressor activity of C3G is independent of its CDC25-homology domain.

7 January 2021

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Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

7 January 2021

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The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation

7 January 2021

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

7 January 2021

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

7 January 2021

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Regulation of actin dynamics by WASP and WAVE family proteins.

7 January 2021

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Linking Rap to cell adhesion

7 January 2021

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Cellular functions of the Rap1 GTP-binding protein: a pattern emerges

7 January 2021

1 reference

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Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Function and regulation of Ena/VASP proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Formin-induced nucleation of actin filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Formins and VASPs may co-operate in the formation of filopodia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Control of the assembly of ATP- and ADP-actin by formins and profilin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The role of thin filopodia in motility and morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Cellular motility driven by assembly and disassembly of actin filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Epithelial morphogenesis: filopodia at work.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Structures in focus--filopodia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Cellular control of actin nucleation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

What is in a filopodium? Starfish versus hedgehogs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Essential roles for the Abl and Arg tyrosine kinases in neurulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Cycling, stressed-out and nervous: cellular functions of c-Abl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

How do Abl family kinases regulate cell shape and movement?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The essential role of profilin in the assembly of actin for microspike formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

p59Hck isoform induces F-actin reorganization to form protrusions of the plasma membrane in a Cdc42- and Rac-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Rho GTPases and the actin cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Regulation of actin dynamics by WASP family proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Biochemical properties and inhibitors of (N-)WASP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The role of profilin complexes in cell motility and other cellular processes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Profilins as regulators of actin dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Profilin as a potential mediator of membrane-cytoskeleton communication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Distribution of profilin in fibroblasts correlates with the presence of highly dynamic actin filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Cell motility: proline-rich proteins promote protrusions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The role of profilin in actin polymerization and nucleotide exchange.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Tumor suppressor activity of profilin requires a functional actin binding site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Distinct roles of profilin in cell morphological changes: microspikes, membrane ruffles, stress fibers, and cytokinesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The Rho family GTPase Rif induces filopodia through mDia2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

c-Abl phosphorylates Dok1 to promote filopodia during cell spreading

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Temporal dissection of beta1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Crk family adaptor proteins trans-activate c-Abl kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Interaction of Bcr/Abl with C3G, an exchange factor for the small GTPase Rap1, through the adapter protein Crkl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.03.019

10.1016/J.YEXCR.2007.03.019

7 January 2021

Identifiers

DOI

1 reference

release_4llhmffaazhohc2wsmbe32b3km

17 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4llhmffaazhohc2wsmbe32b3km

mapped directly with Wikidata item

24 November 2022

based on heuristic

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