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FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance.
scientific article published on January 2006
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scholarly article
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
title
FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
main subject
imatinib
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author
Nicola Brownlow
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
Taylor JR
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Domin J
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Dibb NJ
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
language of work or name
English
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publication date
1 January 2006
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
25
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
1
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
147-151
1 reference
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Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1209007
0 references
cites work
Regulation of microglia - potential new drug targets in the CNS.
1 reference
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A single amino acid exchange inverts susceptibility of related receptor tyrosine kinases for the ATP site inhibitor STI-571.
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Protein kinases--the major drug targets of the twenty-first century?
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7 January 2021
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Several Bcr-Abl kinase domain mutants associated with imatinib mesylate resistance remain sensitive to imatinib
1 reference
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Crossref
reference URL
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7 January 2021
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Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.
1 reference
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Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors
1 reference
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Switching on kinases: oncogenic activation of BRAF and the PDGFR family
1 reference
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Expression of v-fms and c-fms in the hemopoietic cell line FDC-P1.
1 reference
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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
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Management of malignant gastrointestinal stromal tumours
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CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract
1 reference
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Crossref
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Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
1 reference
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Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy
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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
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7 January 2021
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The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
1 reference
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Crossref
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7 January 2021
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Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209007
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7 January 2021
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Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5.
1 reference
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7 January 2021
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Cell specific transformation by c-fms activating loop mutations is attributable to constitutive receptor degradation
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209007
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Directions of drug discovery in osteoporosis
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7 January 2021
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SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
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7 January 2021
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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
1 reference
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7 January 2021
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The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease
1 reference
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7 January 2021
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Role of colony-stimulating factor-1 in reproduction and development
1 reference
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Crossref
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Tumour-educated macrophages promote tumour progression and metastasis
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Class III receptor tyrosine kinases: role in leukaemogenesis
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Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells
1 reference
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Crossref
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A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential
1 reference
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Transforming potential of the c-fms proto-oncogene (CSF-1 receptor).
1 reference
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Crossref
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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase
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Crossref
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The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1
1 reference
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Crossref
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7 January 2021
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Evidence that downregulation of the M-CSF receptor is not dependent upon receptor kinase activity
1 reference
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The v-fms oncogene induces factor-independent growth and transformation of the interleukin-3-dependent myeloid cell line FDC-P1.
1 reference
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Crossref
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Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype
1 reference
stated in
Crossref
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7 January 2021
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Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1209007
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1209007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Dimensions Publication ID
1007897425
0 references
PubMed publication ID
16170366
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16170366
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16170366%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
ResearchGate publication ID
7594130
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