(Q40152988)

18 September 2017

1 reference

title

Nucleic acid adducts of chemical carcinogens and mutagens (English)

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18 September 2017

K. Hemminki

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6347126

4 October 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6347126

4 October 2023

publication date

1 April 1983

1 reference

full work available at URL

18 September 2017

http://link.springer.com/content/pdf/10.1007/BF00316495.pdf

file format

Portable Document Format

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http://link.springer.com/article/10.1007/BF00316495/fulltext.html

4 October 2023

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http://link.springer.com/content/pdf/10.1007/BF00316495

4 October 2023

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4 October 2023

published in

Archives of Toxicology

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18 September 2017

52

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18 September 2017

4

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18 September 2017

249-285

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https://scigraph.springernature.com/pub.10.1007/bf00316495

18 September 2017

0 references

cites work

Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems

1 reference

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The reaction of mono- and di-functional alkylating agents with nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

EFFECTS OF ALKYLATING AGENTS ON T2 AND T4 BACTERIOPHAGES

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Genetic toxicity of some important epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

The alkylation of 2′-deoxyguanosine and of thymidine with diazoalkanes. Some observations on O-alkylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Letter: Chemical structure of QAII, one of the covalently bound adducts of carcinogenic 4-nitroquinoline 1-oxide with nucleic acid bases of cellular nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

The mutagenicity of hydrazine and some of its derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Alkylation by propylene oxide of deoxyribonucleic acid, adenine, guanosine and deoxyguanylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Mutagenic, cancerogenic and teratogenic effects of alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Comparative Studies of the Hepatocarcinogen N,N-Dimethylnitrosamine in vivo: Reaction Sites in Rat Liver DNA and the Significance of their Relative Stabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

The action of mono- and di-functional sulphur mustards on the ribonucleic acid-containing bacteriophage μ2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Main binding sites of the carcinogen, 4-nitroquinoline 1-oxide in nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00316495

Bisulfite-catalyzed transamination of cytosine and cytidine

21 January 2018

1 reference

12 December 2020

Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine

1 reference

12 December 2020

Identification of the persistently bound form of the carcinogen N-acetyl-2-aminofluorene to rat liver DNA in vivo

1 reference

12 December 2020

Modification of DNA by the benzo[a]pyrene metabolite diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1 reference

12 December 2020

Persistent binding of a new reaction product of the carcinogen N-hydroxy-N-2-acetylaminofluorene with guanine in rat liver DNA in vivo

1 reference

12 December 2020

Structural identification of the pyrimidine derivatives formed from N-(deoxyguanosin-8-yl)-2-aminofluorene in aqueous solution at alkaline pH

1 reference

12 December 2020

Kinetics of formation of O6-ethylguanine in, and its removal from liver DNA of rats receiving diethylnitrosamine

1 reference

12 December 2020

Quantitative comparison of covalent aflatoxin-DNA adducts formed in rat and mouse livers and kidneys.

1 reference

12 December 2020

Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon

1 reference

12 December 2020

Binding of Nenzo[ a ]pyrene 7,8-Diol-9,10-Epoxides to DNA, RNA, and Protein of Mouse Skin Occurs with High Stereoselectivity

1 reference

12 December 2020

Modification of ribonucleic acid by chemical carcinogens. VI. Effect of N-2-acetylaminofluorene modification of guanosine on the codon function of adjacent nucleosides in oligonucleotides

1 reference

12 December 2020

Alkylation products of DNA bases by simple epoxides

1 reference

12 December 2020

Mechanism of action of the nitrosoureas--IV. Reactions of bis-chloroethyl nitrosourea and chloroethyl cyclohexyl nitrosourea with deoxyribonucleic acid

1 reference

12 December 2020

Evaluation of genetic risks of alkylating agents: tissue doses in the mouse from air contaminated with ethylene oxide

1 reference

12 December 2020

In vitro reaction of the carcinogen, N-hydroxy-2-naphthylamine, with DNA at the C-8 and N2 atoms of guanine and at the N6 atom of adenine

1 reference

12 December 2020

Mutagenicities of styrene oxide derivatives on bacterial test systems: relationship between mutagenic potencies and chemical reactivity.

1 reference

12 December 2020

The reaction of (±)-7α, 8β-dihydroxy-9β, 10β-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with dna

1 reference

12 December 2020

Alkylation of N2 in deoxyguanosine by dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline.

1 reference

12 December 2020

Alkylation of macromolecules for detecting mutagenic agents

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12 December 2020

Carcinogenesis by aromatic amines

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12 December 2020

Reactions of Nucleic Acids and NucleoDroteins with Formaldehyde

1 reference

12 December 2020

Alkaline opening of imidazole ring of 7-methylguanosine. 2. Further studies on reaction mechanisms and products

1 reference

12 December 2020

The reaction of beta-propiolactone with derivatives of adenine and with DNA.

1 reference

12 December 2020

Formation of the cross-linked base, diguanylethane, in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea

1 reference

12 December 2020

DNA strand scission by benzo[a]pyrene diol epoxides

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12 December 2020

Reaction of guanosine with ethylating agents

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12 December 2020

Reaction of 7-bromomethylbenz[a]anthracene with nucleic acids, polynucleotides, and nucleosides

1 reference

12 December 2020

Crystal structure of a carcinogen:nucleoside adduct

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12 December 2020

The binding of ethyl carbamate to DNA of mouse liver in vivo: the nature of the bound molecule and the site of binding

1 reference

12 December 2020

1,N2-Ethenoguanine and N2,3-ethenoguanine. Synthesis and comparison of the electronic spectral properties of these linear and angular triheterocycles related to the Y bases

1 reference

12 December 2020

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

1 reference

12 December 2020

Benzo( a )pyrene-7,8-dihydrodiol 9,10-Oxide Adenosine and Deoxyadenosine Adducts: Structure and Stereochemistry

1 reference

12 December 2020

Reactivity-selectivity properties of reactions of carcinogenic electrophiles and nucleosides: influence of pH on site selectivity

1 reference

12 December 2020

Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo

1 reference

12 December 2020

Use of the isolated perfused rat liver to study carcinogen-DNA adduct formation from aflatoxin B1 and sterigmatocystin

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12 December 2020

Reactions of formaldehyde with guanosine

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12 December 2020

Alkylation of DNA in rat tissues following administration of streptozotocin

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12 December 2020

Excisability and persistence of benzo(a)pyrene DNA adducts in epithelioid human lung cells

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12 December 2020

Adducts from the reaction of O,O'-diacetyl or O-acetyl derivatives of the carcinogen 4-hydroxyaminoquinoline 1-oxide with purine nucleosides

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12 December 2020

Alkylation of DNA and proteins in mice exposed to vinyl chloride

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12 December 2020

The electronic structure of platinum-guanine complexes

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12 December 2020

The Chemical Modification of Nucleic Acids

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12 December 2020

Phosphotriesters in rat liver deoxyribonucleic acid after the administration of the carcinogen NN-dimethylnitrosamine in vivo

1 reference

12 December 2020

Reaction products of the carcinogen N-hydroxy-4-acetylamino-4'-fluorobiphenyl with DNA in liver and kidney of the rat

1 reference

12 December 2020

Methylation of liver DNA guanine in hydrazine hepatotoxicity: dose-response and kinetic characteristics of 7-methylguanine and O6-methylguanine formation and persistence in rats.

1 reference

12 December 2020

The reaction of trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene with DNA involves attack at the N7-position of guanine moieties

1 reference

12 December 2020

Reaction of N-n-butyl-N-nitrosourea with DNA in vitro

1 reference

12 December 2020

Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan).

1 reference

12 December 2020

Partial persistency of 2-aminofluorene and N-acetyl-2-aminofluorene in rat liver DNA

1 reference

12 December 2020

DNA alkylation and neuro-oncogenesis by 3,3-dimethyl-1-phenyltriazene

1 reference

12 December 2020

Alkylation of polyguanylic acid at the 2-amino group and phosphate by the potent mutagen (+/-)-7beta,8alpha-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1 reference

12 December 2020

Rapid release of carcinogen-guanine adducts from DNA after reaction with N-acetoxy-2-acetylaminofluorene or N-benzoyloxy-N-methyl-4-aminoazobenzene

1 reference

12 December 2020

Analysis and excision of ring-opened phosphoramide mustard-deoxyguanine adducts in DNA

1 reference

12 December 2020

Minor products from the reaction of (+) and (-) benzo[a]-pyrene-anti-diolepoxide with DNA.

1 reference

12 December 2020

Methylation of nucleic acids by 2,2-dichlorovinyl dimethyl phosphate (dichlorvos, DDVP)

1 reference

12 December 2020

Formation of O6-methylguanine by alkylation of rat liver, colon, and kidney DNA following administration of 1,2-dimethylhydrazine

1 reference

12 December 2020

On the mechanism of action of carcinogenic aromatic amines. II. Binding of N-hydroxy-N-acetyl-4-aminobiphenyl to rat-liver nucleic acids in vitro.

1 reference

12 December 2020

Structural consequences of modification of the oxygen atom of guanine in DNA by the carcinogen N-hydroxy-1-naphthylamine

1 reference

12 December 2020

Probable methylation of nucleic acids of mouse colon by 1,2-dimethylhydrazine in vivo

1 reference

12 December 2020

Interactions of vinyl chloride with rat-liver DNA in vivo

1 reference

12 December 2020

The isolation and characterization of 3-(2-carboxyethyl)cytosine following in vitro reaction of β-propiolactone with calf thymus DNA

1 reference

12 December 2020

The in vitro and in vivo reaction at the N7-position of guanine of the ultimate carcinogen derived from benzo[a]pyrene

1 reference

12 December 2020

Guanyl O6-arylamination and O6-arylation of DNA by the carcinogen N-hydroxy-1-naphthylamine

1 reference

12 December 2020

Alkaline opening of imidazole ring of 7-methylguanosine. 1. Analysis of the resulting pyrimidine derivatives

1 reference

12 December 2020

Alteration of the DNA secondary structure in the DNA-polylysine complex evidenced by sodium bisulfite modification

1 reference

12 December 2020

Differential excision from DNA of the C-8 and N2 guanosine adducts of N-acetyl-2-aminofluorene by single strand-specific endonucleases

1 reference

12 December 2020

1 reference

12 December 2020

Studies on methylazoxymethanol, the aglycone of cycasin: methylation of nucleic acids in vitro

1 reference

12 December 2020

Template activity of calf thymus DNA modified by a dihydrodiol epoxide derivative of benzo[a]pyrene

1 reference

12 December 2020

Benzo[a]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA

1 reference

12 December 2020

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo

1 reference

12 December 2020

Correlation of alkylating and mutagenic activities of allyl and allylic compounds: standard alkylation test vs. kinetic investigation.

1 reference

12 December 2020

Excision of DNA damage arising from chemicals of different carcinogenic potencies

1 reference

12 December 2020

Structures of the DNA adducts formed in mouse liver after administration of the proximate hepatocarcinogen 1'-hydroxyestragole

1 reference

12 December 2020

Adducts from the reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with deoxyguanosine or DNA in vitro and from hepatic DNA of mice treated with N-methyl- or N,N-dimethyl-4-aminoazobenzene

1 reference

12 December 2020

The chemical effects of nucleic acid alkylation and their relation to mutagenesis and carcinogenesis

1 reference

12 December 2020

DNA alkylation by vinyl chloride metabolites: etheno derivatives or 7-alkylation of guanine?

1 reference

12 December 2020

Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz( )anthracene and 7-bromomethyl-12-methylbenz( )anthracene with deoxyribonucleic acid in vitro.

1 reference

12 December 2020

Mass spectral characterisation of the major DNA--carcinogen adduct formed from the metabolically activated carcinogen 15,16-dihydro-11-methylcyclopenta[a]phenanthren-17-one

1 reference

12 December 2020

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1 reference

12 December 2020

Inactivation of bacteriophage T7 by mono- and difunctional sulphur mustards in relation to cross-linking and depurination of bacteriophage DNA

1 reference

12 December 2020

Mechanism of action of the nitrosoureas -- III. Reactions of bis-chloroethyl nitrosourea and bis-fluoroethyl nitrosourea with adenosine

1 reference

12 December 2020

Aberrant methylation of liver DNA in rats during hepatotoxicity

1 reference

12 December 2020

Isolation and identification of cross-links from formaldehyde-treated nucleic acids

1 reference

12 December 2020

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas

1 reference

12 December 2020

Diethyl Pyrocarbonate in Nucleic Acid Research

1 reference

12 December 2020

Reactions of the carcinogen N-acetoxy-4-acetamidostilbene with polynucleotides in vitro

1 reference

12 December 2020

Characterization of DNA adducts of the carcinogen N-methyl-4-aminoazobenzene in vitro and in vivo

1 reference

12 December 2020

Reactions of β-propiolactone, β-butyrolactone and γ-butyrolactone with nucleic acids

1 reference

12 December 2020

Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro

1 reference

12 December 2020

Mechanism of benzo[a]pyrene diol epoxide induced deoxyribonucleic acid strand scission

1 reference

12 December 2020

Phosphate diester formation following reaction of beta-propiolactone with thymidine-5'-monophosphoric acid

1 reference

12 December 2020

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1 reference

12 December 2020

Molecular pharmacology of the haloethyl nitrosoureas: formation of 6-hydroxyethylguanine in DNA treated with BCNU (N,N1-bis[2-chloroethyl]-N-nitrosourea)

1 reference

12 December 2020

Mechanism of activation of a human oncogene

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12 December 2020

Identification of guanine-adducts of carcinogens by their fluorescence.

1 reference

12 December 2020

N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo

1 reference

12 December 2020

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver

1 reference

12 December 2020

Alkylation of guanosine and deoxyguanosine by phosphoramide mustard

1 reference

12 December 2020

Fluorescence study of DNA alkylation by epoxides

1 reference

12 December 2020

Chemistry of guanine and its biologically significant derivatives

1 reference

12 December 2020

Reactions of 'bay-region' and non-'bay-region' diol-epoxides of benz(a)anthracene with DNA: evidence indicating that the major products are hydrocarbon-N2-guanine adducts.

1 reference

12 December 2020

Formation of 6-dimethylcarbamyloxy-dGuo, 6-dimethylamino-dGuo and 4-dimethylamino-dThd following in vitro reaction of dimethylcarbamyl chloride with calf thymus DNA and 6-diethylcarbamyloxy-dGuo following in vitro reaction of diethylcarbamyl chlorid

1 reference

12 December 2020

Fluorescent adenosine and cytidine derivatives

1 reference

12 December 2020

Alkylation of RNA by vinyl bromide metabolites in vitro and in vivo

1 reference

12 December 2020

On the reaction kinetics in water of 1,3-propane sultone and 1.4-butane sultone: A comparison of reaction rates and mutagenic activities of some alkylating agents

1 reference

12 December 2020

Alkylated purines in the DNA of various rat tissues after administration of 1,2-dimethylhydrazine

1 reference

12 December 2020

Mechanism of action of the nitrosoureas--1. Role of fluoroethylcytidine in the reaction of bis-fluoroethyl nitrosourea with nucleic acids

1 reference

12 December 2020

Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz(a)anthracene and 7-bromomethyl-12-methylbenz(a)anthracene with mouse skin deoxyribonucleic acid in vivo.

1 reference

12 December 2020

Formation of precancerous islands in rat liver and modification of DNA by ethyl carbamate: implications for its metabolism

1 reference

12 December 2020

Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor

1 reference

12 December 2020

Comparison of alkylation rates and mutagenicity of directly acting industrial and laboratory chemicals: epoxides, glycidyl ethers, methylating and ethylating agents, halogenated hydrocarbons, hydrazine derivatives, aldehydes, thiuram and dithiocarba

1 reference

12 December 2020

Sensitivity of the conformation of deoxyguanosine to binding at the C-8 position by N-acetylated and unacetylated 2-aminofluorene

1 reference

12 December 2020

The reaction of guanosine and deoxyguanosine with glycidaldehyde

1 reference

12 December 2020

The preparation and properties of N-hydroxyethyl derivatives of adenosine, adenosine triphosphate, and nicotinamide adenine dinucleotide

1 reference

12 December 2020

Specificity of the interaction of DNA-platinum, amount of platinum, and pH measurement

1 reference

12 December 2020

Aflatoxin B -oxide generated by chemical or enzymic oxidation of aflatoxin B1 causes guanine substitution in nucleic acids

1 reference

12 December 2020

Adducts between the carcinogen 2-acetamidophenanthrene and adenine and guanine of DNA

1 reference

12 December 2020

Modification of deoxyguanosine by chloroethylene oxide

1 reference

12 December 2020

Identification of 7-carboxymethylguanine in DNA from pancreatic acinar cells exposed to azaserine

1 reference

12 December 2020

Metabolism of benzo(a)pyrene, N-nitrosodimethylamine, and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus

1 reference

12 December 2020

A quantitative determination of the covalent binding of a series of polycylic hydrocarbons to DNA in mouse skin

1 reference

12 December 2020

Dimethylnitrosamine adducts excreted in rat urine

1 reference

12 December 2020

Differences in the binding of 2-Acetylaminofluorene and its N-Hydroxy metabolite to liver nucleic acids of male and female rats

1 reference

12 December 2020

A new method for sequencing DNA

1 reference

12 December 2020

Structure-activity relationship in halogen and alkyl substituted allyl and allylic compounds: correlation of alkylating and mutagenic properties.

1 reference

12 December 2020

Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

1 reference

12 December 2020

Alkylation of RNA by vinyl chloride metabolites in vitro and in vivo: formation of 1-N(6)-etheno-adenosine

1 reference

12 December 2020

Chemical carcinogenesis

1 reference

12 December 2020

Reactions of cytidine with 7-bromomethylbenz[a]anthracene, benzyl bromide, and p-methoxybenzyl bromide. Ratio of amino to 3 substitution

1 reference

12 December 2020

Novel assay of 7-alkylation of guanine residues in DNA. Application to nitrogen mustard, triethylenemelamine and mitomycin C

1 reference

12 December 2020

Effects of beta-Hydroxyethylation and beta-Methoxyethylation on DNA in vitro

1 reference

12 December 2020

DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells

1 reference

12 December 2020

CROSSLINKING OF DNA BY ENZYMATICALLY OR CHEMICALLY ACTIVATED MITOMYCINS AND PORFIROMYCINS, BIFUNCTIONALLY "ALKYLATING" ANTIBIOTICS

1 reference

12 December 2020

Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.

1 reference

12 December 2020

Mutagenic potential of allyl and allylic compounds. Structure-activity relationship as determined by alkylating and direct in vitro mutagenic properties.

1 reference

12 December 2020

Reactions of the carcinogen N-acetoxy-4-acetamidostilbene with nucleosides

1 reference

12 December 2020

Alkylation of guanosine and 4-(p-nitrobenzyl)-pyridine by styrene oxide analogues in vitro

1 reference

12 December 2020

Henry Ford Hospital medical journal

1

22

35

MD Anderson

1974

1 reference

Biochimica et Biophysica Acta

4 October 2023

79

355

177

E Kriek

1974

1 reference

4 October 2023

Federation Proceedings

168

23

946

W Szybalski

1964

1 reference

4 October 2023

Identifiers

DOI

10.1007/BF00316495

1 reference

18 September 2017

1 reference