(Q40157240)

18 September 2017

Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B. (English)

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18 September 2017

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Liu H

1

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18 September 2017

Zhou Y

2

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18 September 2017

Boggs SE

3

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18 September 2017

Belinsky SA

4

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18 September 2017

Liu J

5

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18 September 2017

language of work or name

English

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publication date

19 March 2007

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18 September 2017

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18 September 2017

26

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18 September 2017

40

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18 September 2017

5900-5910

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210400

18 September 2017

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cites work

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

1 reference

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7 January 2021

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

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7 January 2021

Gene-promoter hypermethylation as a biomarker in lung cancer

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7 January 2021

DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy

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7 January 2021

Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary

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7 January 2021

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.

1 reference

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7 January 2021

In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins

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7 January 2021

Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

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7 January 2021

Regulation of DNA methylation in human breast cancer. Effect on the urokinase-type plasminogen activator gene production and tumor invasion

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Tobacco smoke carcinogens and lung cancer

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7 January 2021

Biochemistry and biology of mammalian DNA methyltransferases

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7 January 2021

Cancer statistics, 2002

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7 January 2021

Identification, localization and characterization of the human gamma-synuclein gene.

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7 January 2021

Overexpression of synuclein-gamma in pancreatic adenocarcinoma

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7 January 2021

Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Loss of epigenetic control of synuclein-gamma gene as a molecular indicator of metastasis in a wide range of human cancers

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7 January 2021

Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells

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7 January 2021

Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences

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7 January 2021

Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.

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7 January 2021

Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke

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7 January 2021

CpG sites preferentially methylated by Dnmt3a in vivo

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7 January 2021

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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7 January 2021

Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis

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7 January 2021

DNA methyltransferase and demethylase in human prostate cancer

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7 January 2021

Preferential binding of DNA methyltransferase and increased de novo methylation of deoxyinosine containing DNA

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7 January 2021

Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Targeting the epigenome for the treatment and prevention of lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210400

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210400

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Dimensions Publication ID

18 September 2017

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1 reference