(Q40435113)

English

Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

apoptotic process

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hypermethylation

1 reference

based on heuristic

inferred from title

author name string

Kevin Pruitt

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Aylin S Ulkü

2

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Europe PubMed Central

PubMed publication ID

20 September 2017

Karen Frantz

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Rafael J Rojas

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Vanessa M Muniz-Medina

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Vivek M Rangnekar

6

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Channing J Der

7

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Janiel M Shields

8

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Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

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publication date

14 April 2005

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Europe PubMed Central

PubMed publication ID

20 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

20 September 2017

280

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Europe PubMed Central

PubMed publication ID

20 September 2017

24

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Europe PubMed Central

PubMed publication ID

20 September 2017

23363-23370

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Europe PubMed Central

PubMed publication ID

20 September 2017

Apoptosis: implications of basic research for clinical oncology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Mitochondria in apoptosis and human disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Apoptotic DNA fragmentation and tissue homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Oncogenic Ras sensitizes cells to apoptosis by Par-4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Understanding Ras: 'it ain't over 'til it's over'.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Ras signalling and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

The dark side of Ras: regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Suppression of Ras-induced apoptosis by the Rac GTPase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Ral-GTPases: approaching their 15 minutes of fame

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Cell signaling: life or death decisions of ras proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Distinct requirements for Ras oncogenesis in human versus mouse cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Analysis of the transcriptional program induced by Raf in epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Altering gene expression with 5-azacytidine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Targeting RAS signalling pathways in cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Vav2 is an activator of Cdc42, Rac1, and RhoA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

DNA methylation, chromatin inheritance, and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Characterization of the human DNA methyltransferase splice variant Dnmt1b

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Regulation of DNA methylation by the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503083200

21 January 2018

Identifiers

10.1074/JBC.M503083200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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