(Q40928369)

English

Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras.

scientific article published on August 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

V Gire

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

C J Marshall

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

D Wynford-Thomas

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 August 1999

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

4819-4832

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade

1 reference

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21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

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21 January 2018

Proteins regulating Ras and its relatives

1 reference

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21 January 2018

Spontaneous de-differentiation correlates with extended lifespan in transformed thyroid epithelial cells: an epigenetic mechanism of tumour progression?

1 reference

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21 January 2018

Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation.

1 reference

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21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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21 January 2018

Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells

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21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

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21 January 2018

A genetic model for colorectal tumorigenesis

1 reference

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21 January 2018

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

1 reference

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21 January 2018

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

1 reference

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21 January 2018

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

1 reference

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21 January 2018

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

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21 January 2018

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

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21 January 2018

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

1 reference

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21 January 2018

Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells

1 reference

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21 January 2018

Autocrine stimulation after transfer of the granulocyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway

1 reference

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21 January 2018

Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection

1 reference

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21 January 2018

Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

1 reference

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21 January 2018

Mitogen-activated protein (MAP) kinase phosphorylation of MAP kinase kinase: determination of phosphorylation sites by mass spectrometry and site-directed mutagenesis

1 reference

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21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

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21 January 2018

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21 January 2018

A method for incorporating macromolecules into adherent cells.

1 reference

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21 January 2018

RalGDS functions in Ras- and cAMP-mediated growth stimulation

1 reference

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21 January 2018

Differential effects of protein kinase A on Ras effector pathways

1 reference

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21 January 2018

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 reference

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21 January 2018

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

1 reference

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21 January 2018

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade

1 reference

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21 January 2018

An essential role for Rac in Ras transformation

1 reference

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21 January 2018

A role for Rho in Ras transformation

1 reference

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21 January 2018

raf family serine/threonine protein kinases in mitogen signal transduction.

1 reference

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21 January 2018

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

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21 January 2018

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

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21 January 2018

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

1 reference

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21 January 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

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21 January 2018

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

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21 January 2018

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.

1 reference

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21 January 2018

Biochemical and biological properties of the human N-ras p21 protein

1 reference

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21 January 2018

Regulation of transcription by MAP kinase cascades

1 reference

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A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

1 reference

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Multiple Ras functions can contribute to mammalian cell transformation

1 reference

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A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

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Loss of dependence on IGF-1 for proliferation of human thyroid adenoma cells

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Oncogenes and anti-oncogenes; the molecular basis of tumour behaviour

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Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth

1 reference

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21 January 2018

Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras

1 reference

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Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

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Transformation of mammalian cells by constitutively active MAP kinase kinase

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Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

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Nutrition and oral cancer

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Characterization of the prtA and prtB genes of Erwinia chrysanthemi EC16.

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Identifiers

10.1038/SJ.ONC.1202857

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

ResearchGate publication ID

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