(Q40159476)

English

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations

scientific article published on April 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

1 reference

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1 reference

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Vernon E Walker

9

object named as

Vernon E Walker

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

2

object named as

Dale M Walker

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Miriam C. Poirier

8

object named as

Miriam C Poirier

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

7

object named as

Ofelia A Olivero

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Meghan M Carter

3

object named as

Meghan M Carter

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Consuelo L McCash

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object named as

Consuelo L McCash

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Edmund M Cordova

6

object named as

Edmund M Cordova

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

author name string

Salina M Torres

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Dennis L Cook

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

publication date

1 April 2007

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Environmental and Molecular Mutagenesis

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Europe PubMed Central

PubMed publication ID

18 September 2017

48

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Europe PubMed Central

PubMed publication ID

18 September 2017

3-4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

224-238

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Age dependent selection against HPRT deficient T lymphocytes in the HPRT+/- heterozygous mouse.

1 reference

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Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression in vitro

1 reference

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Analysis of mutations in the Tk gene of Tk(+/-) mice treated as neonates with 3'-azido-3'-deoxythymidine (AZT).

1 reference

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21 January 2018

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

1 reference

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21 January 2018

Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

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7 January 2021

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Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage

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Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues

1 reference

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Malignancy-related causes of death in human immunodeficiency virus-infected patients in the era of highly active antiretroviral therapy

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Pharmacotherapy of perinatal HIV.

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Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.

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7 January 2021

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Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy

1 reference

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7 January 2021

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Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

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7 January 2021

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Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence?

1 reference

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7 January 2021

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Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir

1 reference

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7 January 2021

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Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

1 reference

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7 January 2021

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

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7 January 2021

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Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326

1 reference

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7 January 2021

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Factors that affect the frequency of thioguanine-resistant lymphocytes in mice following exposure to ethylnitrosourea

1 reference

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7 January 2021

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Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

1 reference

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7 January 2021

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Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

1 reference

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7 January 2021

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Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Effect of two different combinations of antiretrovirals (AZT+ddI and AZT+3TC) on cytokine production and apoptosis in asymptomatic HIV infection

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

inferred from DOI database lookup

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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The triple combination indinavir-zidovudine-lamivudine is highly synergistic

1 reference

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7 January 2021

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Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

https://api.crossref.org/works/10.1002%2FEM.20264

7 January 2021

based on heuristic

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Transplacental mutagenicity of N-ethyl-N-nitrosourea at the hprt locus in T-lymphocytes of exposed B6C3F1 mice

1 reference

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7 January 2021

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Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine

1 reference

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Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine

1 reference

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Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine

1 reference

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Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea

1 reference

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Genetic risks of antiviral nucleoside analogues--a survey

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10.1002/EM.20264

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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