(Q40168851)

English

The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation

scientific article published on 17 May 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

18 September 2017

The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation (English)

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Europe PubMed Central

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18 September 2017

viral nucleocapsid

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based on heuristic

inferred from title

4

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13 June 2020

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13 June 2020

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Zhen Ding

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13 June 2020

Liurong Fang

2

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13 June 2020

Shuangling Yuan

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13 June 2020

Xunlei Wang

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13 June 2020

Siwen Long

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13 June 2020

Mohan Wang

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13 June 2020

Dang Wang

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13 June 2020

Shaobo Xiao

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13 June 2020

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17 May 2017

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18 September 2017

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13 June 2020

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13 June 2020

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13 June 2020

49655-49670

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13 June 2020

The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination

1 reference

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1 reference

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Porcine deltacoronavirus (PDCoV) infection suppresses RIG-I-mediated interferon-β production

1 reference

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Molecular pathology of emerging coronavirus infections

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Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor

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Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1.

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The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

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Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment.

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Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.

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Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

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The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

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Multiple sensors ensure guide strand selection in human RNAi pathways

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Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

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Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

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Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model

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SARS-CoV regulates immune function-related gene expression in human monocytic cells.

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Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

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RIG-I like receptors in antiviral immunity and therapeutic applications

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Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons

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Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

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Triggering the interferon antiviral response through an IKK-related pathway

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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A major outbreak of severe acute respiratory syndrome in Hong Kong

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22 September 2017

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1 reference

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22 September 2017

Modular structure of PACT: distinct domains for binding and activating PKR

1 reference

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PACT, a protein activator of the interferon-induced protein kinase, PKR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

22 September 2017

Interferon Action III. The Rate of Primary Transcription of Vesicular Stomatitis Virus is Inhibited by Interferon Action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

22 September 2017

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

25 September 2017

PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

25 September 2017

Sequence comparison of the N genes of five strains of the coronavirus mouse hepatitis virus suggests a three domain structure for the nucleocapsid protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

17 June 2018

Increased interaction between PACT molecules in response to stress signals is required for PKR activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

20 August 2018

Organizations and promoter analyses of the human and the mouse genes for PACT, the protein-activator of the interferon-induced protein kinase, PKR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5564796

20 August 2018

Nidovirales: a new order comprising Coronaviridae and Arteriviridae

1 reference

https://pubmed.ncbi.nlm.nih.gov/28591694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

1 reference

https://pubmed.ncbi.nlm.nih.gov/28591694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proceedings of the VIII International Symposium on Nidoviruses (Coronaviruses and Arteriviruses). May 20-25, 2000. Lake Harmony, Pennsylvania, USA

1 reference

https://pubmed.ncbi.nlm.nih.gov/28591694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.17912

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28591694%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28591694%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28591694%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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