(Q40707626)

English

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3.

scientific article published on 20 April 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

22 September 2017

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. (English)

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Middle East respiratory syndrome coronavirus

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phosphorylation

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based on heuristic

inferred from title

Middle East respiratory syndrome

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Lok Yin Roy Wong

2

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Europe PubMed Central

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4 June 2020

5

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4 June 2020

7

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4 June 2020

8

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4 June 2020

10

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4 June 2020

author name string

Cheuk-Lai Fung

3

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4 June 2020

Kam-Leung Siu

4

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4 June 2020

Kit-San Yuen

6

1 reference

Europe PubMed Central

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4 June 2020

Kwok-Yung Yuen

9

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Europe PubMed Central

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4 June 2020

publication date

20 April 2016

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22 September 2017

Emerging Microbes & Infections

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

5

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

e39

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4855074/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1038/emi.2016.33

0 references

A molecular arms race between host innate antiviral response and emerging human coronaviruses

1 reference

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25 September 2017

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

1 reference

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Suppression of type I and type III IFN signalling by NSs protein of severe fever with thrombocytopenia syndrome virus through inhibition of STAT1 phosphorylation and activation

1 reference

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25 September 2017

Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control

1 reference

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25 September 2017

Spread of MERS to South Korea and China

1 reference

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Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease

1 reference

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25 September 2017

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

1 reference

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Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease

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Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

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To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion.

1 reference

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25 September 2017

A case of imported Middle East Respiratory Syndrome coronavirus infection and public health response, Greece, April 2014.

1 reference

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Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?

1 reference

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25 September 2017

Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855074

25 September 2017

Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain.

1 reference

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Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

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25 September 2017

The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

1 reference

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25 September 2017

Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease

1 reference

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Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

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25 September 2017

The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

1 reference

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25 September 2017

Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment.

1 reference

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Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.

1 reference

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25 September 2017

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist

1 reference

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25 September 2017

Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread

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Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

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25 September 2017

Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures

1 reference

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25 September 2017

Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus

1 reference

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Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

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25 September 2017

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

1 reference

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

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25 September 2017

Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity

1 reference

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SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

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25 September 2017

MIP-T3 is a negative regulator of innate type I IFN response

1 reference

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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

1 reference

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A structural analysis of M protein in coronavirus assembly and morphology

1 reference

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Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

1 reference

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Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

1 reference

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Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

1 reference

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Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

1 reference

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IKK-i signals through IRF3 and NFkappaB to mediate the production of inflammatory cytokines

1 reference

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 reference

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 reference

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

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25 September 2017

Cell type-specific involvement of RIG-I in antiviral response

1 reference

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

1 reference

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25 September 2017

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855074

25 September 2017

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

1 reference

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Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

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Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome

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Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response.

1 reference

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First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013.

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The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

1 reference

https://pubmed.ncbi.nlm.nih.gov/27094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities -

1 reference

https://pubmed.ncbi.nlm.nih.gov/27094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe respiratory illness associated with a novel coronavirus--Saudi Arabia and Qatar, 2012

1 reference

https://pubmed.ncbi.nlm.nih.gov/27094905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/EMI.2016.33

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094905%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

ResearchGate publication ID

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