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IRE1α promotes viral infection by conferring resistance to apoptosis.
scientific article published on 6 June 2017
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
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22 March 2020
title
IRE1α promotes viral infection by conferring resistance to apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
author
Susan L Fink
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1
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
Ryan D Molony
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3
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
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22 March 2020
Takao Iwawaki
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4
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
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22 March 2020
Akiko Iwasaki
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7
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5535312
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22 March 2020
Brett Lindenbach
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6
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Brett D Lindenbach
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Europe PubMed Central
PMC publication ID
5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
author name string
Teshika R Jayewickreme
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2
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Europe PubMed Central
PMC publication ID
5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
Charles S Landis
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5
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
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22 March 2020
publication date
6 June 2017
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Europe PubMed Central
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5535312
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retrieved
22 March 2020
published in
Science Signaling
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
volume
10
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Europe PubMed Central
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5535312
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
issue
482
1 reference
stated in
Europe PubMed Central
PMC publication ID
5535312
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
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IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
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IRE1α activation protects mice against acetaminophen-induced hepatotoxicity
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Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.
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The unfolded protein response: integrating stress signals through the stress sensor IRE1α
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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.
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The mitochondrial antiviral signaling protein, MAVS, is cleaved during apoptosis
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Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-beta induction via X-box binding protein 1.
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IRE1 signaling affects cell fate during the unfolded protein response
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Maintenance of endoplasmic reticulum (ER) homeostasis in herpes simplex virus type 1-infected cells through the association of a viral glycoprotein with PERK, a cellular ER stress sensor.
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The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice
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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response
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Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
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17 June 2018
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
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Caspase-3-like proteases are activated by infection but are not required for replication of vesicular stomatitis virus
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17 June 2018
Viruses and apoptosis
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17 June 2018
An essential role in liver development for transcription factor XBP-1
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17 June 2018
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
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retrieved
17 June 2018
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
17 June 2018
Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
17 June 2018
miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer via targeting BCL2, BCL2L12 and MCL1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
Inhibition of microRNA-125a promotes human endothelial cell proliferation and viability through an antiapoptotic mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
The acidic domain of hepatitis C virus NS4A contributes to RNA replication and virus particle assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
Requirement of caspase-3 for efficient apoptosis induction and caspase-7 activation but not viral replication or cell rounding in cells infected with vesicular stomatitis virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5535312
retrieved
20 August 2018
Identifiers
DOI
10.1126/SCISIGNAL.AAI7814
1 reference
stated in
Europe PubMed Central
PMC publication ID
5535312
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
PMC publication ID
5535312
1 reference
stated in
Europe PubMed Central
PMC publication ID
5535312
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
PubMed publication ID
28588082
1 reference
stated in
Europe PubMed Central
PMC publication ID
5535312
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28588082%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 March 2020
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