(Q40171781)

18 September 2017

p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

18 September 2017

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author name string

Jozsef Gal

1

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18 September 2017

Anna-Lena Ström

2

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18 September 2017

Renee Kilty

3

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18 September 2017

Fujian Zhang

4

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18 September 2017

Haining Zhu

5

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18 September 2017

language of work or name

English

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publication date

12 February 2007

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Journal of Biological Chemistry

18 September 2017

10

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based on heuristic

inferred from page(s)

published in

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18 September 2017

282

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18 September 2017

15

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18 September 2017

11068-11077

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Unraveling the mechanisms involved in motor neuron degeneration in ALS

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Pathogenic superoxide dismutase structure, folding, aggregation and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Murine peritoneal macrophages induce a novel 60-kDa protein with structural similarity to a tyrosine kinase p56lck-associated protein in response to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Inhibition of sequestosome 1/p62 up-regulation prevents aggregation of ubiquitinated proteins induced by prostaglandin J2 without reducing its neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Aggresomes, inclusion bodies and protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Hassles with taking out the garbage: aggravating aggresomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Evidence for p62 aggregate formation: role in cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Misfolded CuZnSOD and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

Structure and functional properties of the ubiquitin binding protein p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

NF-kappa B: a crucial transcription factor for glial and neuronal cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608787200

21 January 2018

Identifiers

DOI

10.1074/JBC.M608787200

1 reference

18 September 2017

1 reference