(Q40179739)

18 September 2017

Paclitaxel-2'-Ethylcarbonate prodrug can circumvent P-glycoprotein-mediated cellular efflux to increase drug cytotoxicity (English)

1 reference

18 September 2017

4

Fumitaka Kikkawa

1 reference

18 September 2017

Tadatoshi Tanino

1

1 reference

18 September 2017

Akihiro Nawa

2

1 reference

18 September 2017

Eisaku Kondo

3

1 reference

18 September 2017

Tohru Daikoku

5

1 reference

18 September 2017

Tatsuya Tsurumi

6

1 reference

18 September 2017

Chenhong Luo

7

1 reference

18 September 2017

Yukihiro Nishiyama

8

1 reference

18 September 2017

Yuki Takayanagi

9

1 reference

18 September 2017

Katuhiko Nishimori

10

1 reference

18 September 2017

Seiji Ichida

11

1 reference

18 September 2017

Tetsuyuki Wada

12

1 reference

18 September 2017

Yasuyoshi Miki

13

1 reference

18 September 2017

Masahiro Iwaki

14

1 reference

18 September 2017

1 March 2007

1 reference

18 September 2017

Pharmaceutical Research

1 reference

18 September 2017

24

1 reference

18 September 2017

555-565

1 reference

18 September 2017

3

1 reference

Human liver microsomal metabolism of paclitaxel and drug interactions

18 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9171-6

Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9171-6

Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.

21 January 2018

2 references

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9171-6

21 January 2018

12 December 2020

Phase I study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies.

1 reference

12 December 2020

P-glycoprotein binding and modulation of the multidrug-resistant phenotype by estramustine

1 reference

12 December 2020

Characterization of inhibitors of specific carboxylesterases: development of carboxylesterase inhibitors for translational application

1 reference

12 December 2020

Prodrug activation enzymes in cancer gene therapy

1 reference

12 December 2020

A phosphoglycoprotein associated with taxol resistance in J774.2 cells.

1 reference

12 December 2020

Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance

1 reference

12 December 2020

Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells

1 reference

12 December 2020

Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro.

1 reference

12 December 2020

Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2)

1 reference

12 December 2020

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

1 reference

12 December 2020

Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats

1 reference

12 December 2020

Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations

1 reference

12 December 2020

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A

1 reference

12 December 2020

Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.

1 reference

12 December 2020

Effects of paclitaxel on the growth of normal, polyposis, and cancerous human colonic epithelial cells

1 reference

12 December 2020

MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells

1 reference

12 December 2020

Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds

1 reference

12 December 2020

Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1.

1 reference

12 December 2020

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

1 reference

12 December 2020

Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics

1 reference

12 December 2020

Characterization of CPT-11 converting carboxylesterase activity in colon tumor and normal tissues: comparison with p-nitro-phenylacetate converting carboxylesterase activity

1 reference

12 December 2020

Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells

1 reference

12 December 2020

Paclitaxel (175 mg/m2 over 3 hours) with cisplatin or carboplatin in previously untreated ovarian cancer: an interim analysis

1 reference

12 December 2020

Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer

1 reference

12 December 2020

Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2

1 reference

12 December 2020

Phase I trial of intraperitoneal taxol: a Gynecoloic Oncology Group study

1 reference

12 December 2020

Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery

1 reference

12 December 2020

DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo

1 reference

12 December 2020

Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy

1 reference

12 December 2020

Characterization of a human myeloid leukemia cell line highly resistant to taxol

1 reference

12 December 2020

Kinetics of P-glycoprotein-mediated efflux of paclitaxel

1 reference

12 December 2020

The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel.

1 reference

12 December 2020

Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients.

1 reference

12 December 2020

Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells

1 reference

12 December 2020

Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11).

1 reference

12 December 2020

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

1 reference

12 December 2020

Taxol: pharmacology, metabolism and clinical implications.

1 reference

12 December 2020

10.1007/S11095-006-9171-6

Identifiers

DOI

1 reference

18 September 2017

1 reference