(Q40182298)

18 September 2017

Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123). (English)

1 reference

18 September 2017

Gabriella D'Arcangelo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Beth Crowell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Gum Hwa Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ina Nikolaeva

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Valentina Dal Pozzo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

22 October 2015

1 reference

18 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4676199/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The neurology of mTOR

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MEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR.

22 September 2017

1 reference

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FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity

22 September 2017

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Dab1 is required for synaptic plasticity and associative learning

22 September 2017

1 reference

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Evolving neurobiology of tuberous sclerosis complex

22 September 2017

1 reference

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Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells

22 September 2017

1 reference

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Fetal brain mTOR signaling activation in tuberous sclerosis complex

22 September 2017

1 reference

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Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse.

22 September 2017

1 reference

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Targeted treatment trials for tuberous sclerosis and autism: no longer a dream

22 September 2017

1 reference

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The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex.

22 September 2017

1 reference

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Tuberous sclerosis and epilepsy: role of astrocytes

22 September 2017

1 reference

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Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex

22 September 2017

1 reference

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GABAergic interneuron development and function is modulated by the Tsc1 gene

22 September 2017

1 reference

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Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.

22 September 2017

1 reference

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mTOR: A pathogenic signaling pathway in developmental brain malformations

22 September 2017

1 reference

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Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

22 September 2017

1 reference

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Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex

22 September 2017

1 reference

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Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.

22 September 2017

1 reference

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mTOR signaling at a glance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse

22 September 2017

1 reference

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A complex interplay between Akt, TSC2 and the two mTOR complexes

22 September 2017

1 reference

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Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function

22 September 2017

1 reference

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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4676199

Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.

22 September 2017

1 reference

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A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival

22 September 2017

1 reference

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Neuropathology of tuberous sclerosis

22 September 2017

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Subregion- and cell type-restricted gene knockout in mouse brain

22 September 2017

1 reference

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Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions

22 September 2017

1 reference

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Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia

20 August 2018

1 reference

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Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1.

20 August 2018

1 reference

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Generation of a conditional disruption of the Tsc2 gene

20 August 2018

1 reference

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Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.

20 August 2018

1 reference

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Tuberous sclerosis: a primary pathology of astrocytes?

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26693177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/ENEURO.0046-15.2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

26693177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693177%20AND%20SRC:MED&resulttype=core&format=json